Agilent AdvanceBio α(1-3,4,6)- Galactosidase, Recombinant

Technical Note 36 Analysis of Exoglycosidase Digestions of N-Linked Oligosaccharides Using HPAE-PAD INTRODUCTION Analysis of protein glycosylation is an important part of glycoprotein characterization. Oligosaccharides can be linked to a protein through a serine or a threonine as O-linked glycans,…

Application Note Pharma & Biopharma A Workflow for Rapid Sample Preparation and Exoglycosidase Characterization of N-Glycans in Antibodies Authors Yongjing Xie, Letícia Martins Mota, and Michael Butler National Institute for Bioprocessing Research and Training (NIBRT), Foster Avenue, Mount Merrion, Blackrock,…

APPLICATION NOTE 21651 Comprehensive protein glycosylation comparison of an innovator monoclonal antibody to a candidate biosimilar by HILIC UHPLC analysis Authors Silvia Millán, Anne Trappe, Amy Farrell, and Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for…

APPLICATION NOTE 21652 Fast profiling of the N-glycan population in biotherapeutic antibodies by UHPLC-FLD with MS confirmation Authors Silvia Millán, Stefan Mittermayr, Amy Farrell, and Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing Research and…