Comprehensive protein glycosylation comparison of an innovator monoclonal antibody to a candidate biosimilar by HILIC UHPLC analysis

APPLICATION NOTE 21652 Fast profiling of the N-glycan population in biotherapeutic antibodies by UHPLC-FLD with MS confirmation Authors Silvia Millán, Stefan Mittermayr, Amy Farrell, and Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing Research and…

APPLICATION NOTE 21683 An ultrafast, batch-to-batch comparison of monoclonal antibody glycosylation Authors Silvia Millán, Stefan Mittermayr, Amy Farrell, and Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing Research and Training, Dublin, Ireland Keywords NIBRT, Biopharmaceutical,…

Biopharmaceutical Characterisation Compendium A complete toolbox of techniques, workflows and technologies for comprehensive biopharmaceutical characterisation Please click the circles to navigate INTRODUCTION AGGREGATE ANALYSIS CHARGE VARIANT ANALYSIS PEPTIDE MAPPING GLYCANS INTACT AND SUBUNIT ANALYSIS INTRODUCTION The resources collected in this…

APPLICATION NOTE 22060 Understanding the effects of column temperature on high resolution glycan separations Authors: Zoltan Szabo, Thermo Fisher Scientific, Sunnyvale, CA, USA Kean Woodmansey, Thermo Fisher Scientific, Runcorn, United Kingdom Stacy Tremintin, Thermo Fisher Scientific, Sunnyvale, CA, USA Keywords:…