Determination of Hydrodynamic Radius With MaxPeak Premier Protein SEC Columns

Application Note Waters ACQUITY and XBridge Premier Protein SEC 250 Å Columns: A New Benchmark in Inert SEC Column Design Lavelay Kizekai, Matthew A. Lauber Waters Corporation Abstract One of the major limitations in protein size-exclusion chromatography (SEC) is the…

Application Note Evaluation of SEC-MALS Data Quality with Premier Protein SEC Columns Hua Yang, Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract Size Exclusion Chromatography (SEC) coupled with multiangle light scattering (MALS) and UV/RI detection has been increasingly used…

Application Note Modern Size-Exclusion Chromatography Separations of Biosimilar Antibodies at Physiological pH and Ionic Strength Stephan M. Koza, Hua Yang, Ying Qing Yu Waters Corporation Abstract The state of protein derived self-associated, aggregated, and fragmented impurities in therapeutics are critical…

W H I T E PA P E R WP1618: Enhanced SEC-MALS analysis of therapeutic mAbs, biosimilars and AAVs with XBridge Premier columns Leo Liu, Ph.D., Waters | Wyatt Technology Summary SEC-MALS is widely used for the characterization of biopharmaceuticals.…