TIDES 2021: BioAccord with UNIFI for Oligonucleotide Identity, Assay, Purity and Impurities Quantification

Application Note Workflow for Profiling Impurities in Synthetic Oligonucleotides Using the BioAccord™ LCMS System with waters_connect™ Informatics Kellen DeLaney, Jo-Anne Riley, Jonathan Fox, Heidi Gastall, Laetitia Denbigh, Ying Qing Yu Waters Corporation This is an Application Brief and does not…

Application Note Rapid LC-UV/MS Workflow for Routine Oligonucleotide Impurity Monitoring Using the SQ Detector 2 Mass Detector and Empower™ Chromatography Data System (CDS) Henry Foddy, Victoria van Kuijk, Jo-Anne Riley, Cristian Cojocariu Waters Corporation, Wilmslow, United Kingdom Published on August…

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…

Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology Analytical Solutions Using MaxPeak High Performance Surfaces (HPS) Technology for Biopharmaceutical Therapeutics Biopharmaceutical therapeutics have consistently been the fastest growing segment within the pharmaceutical space and require advances…