Rapid Analysis of Synthetic mRNA Cap Structure using Ion Pairing Reversed Phase Liquid Chromatography coupled to Mass Spectrometry

Application Note Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS System Jennifer M. Nguyen, Siu-Hong Chan, Bijoyita Roy, Martin Gilar, Brett Robb, Weibin Chen, Matthew A. Lauber Waters Corporation, New England Biolabs Inc. Abstract…

Application Note Biopharma/Pharma Determining mRNA Capping with HILIC-MS on a Low-Adsorption Flow Path Limiting interfering interactions with metal using the Agilent 1290 Infinity II Bio LC System Authors Gerd Vanhoenacker, Kris Morreel, Stefanie Jonckheere, Pat Sandra, and Koen Sandra RIC…

Application note | 001108 Biopharma Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Authors Goal Robert L Ross, Keeley Murphy, Yi Zhang, To develop a sensitive and robust LC-HRAM-MS/MS method…

Application Note Analysis of mRNA Cap Impurity Profiles and Capping Efficiency Using RapiZyme™ MC1 Ribonuclease Balasubrahmanyam Addepalli, Tatiana Johnston, Catalin Doneanu, Jamuna Vaishnav, Alexandre Gomes, Christian Reidy, Ying Qing Yu, Matthew A. Lauber Waters Corporation, United States Published on June…