Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution

Application note | 001183 Biopharma Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Authors Application benefits Robert L. Ross1, Jenny England2, Rhonda • Confident identification and sequence confirmation of polyadenylated tails in synthetic…

Biopharmaceuticals Analytical solutions for mRNA vaccines and therapeutics Table of contents mRNA vaccines and therapeutics mRNA characterization Lipid nanoparticle characterization Critical quality attributes of mRNA therapeutics Direct mRNA sequence confirmation LNP composition analysis by LC-CAD Optimize impurity analysis with ease…

Customer application note | 000723 Biotechnology mRNA direct sequence mapping using automated partial digestion with magnetic nuclease and LC-HRMS Authors Application benefits Mark Dickman1, Christina Vanhinsbergh1, Jon Bardsley , Ken Cook , Andrew 2 2 Williamson2, Jennifer Sutton3, Keeley Murphy3…

Application note | 002601 Biopharma Confident intact mass analysis of the tRNA isodecoders of phenylalanine by UHPLC-HRAM-MS and BioPharma Finder software Application benefits Authors Robert L. Ross1, Keeley Murphy1, • Confident and sensitive identification of biological transfer ribonucleic acid (tRNA)…