Analysis of Monoclonal Antibody Digests with the Agilent 1290 Infinity 2D-LC Solution Part 2: HILIC × RPLC-MS

Analysis of Monoclonal Antibody Digests with the Agilent 1290 Infinity 2D-LC Solution Application Note Biotherapeutics & Biosimilars Authors Abstract Gerd Vanhoenacker, Koen Sandra, Protein biopharmaceuticals such as monoclonal antibodies and recombinant Isabel Vandenheede, Frank David, and proteins are currently in…

Identifying Monoclonal Antibody Mutation Sites Using the Agilent 1290 Infinity II 2D-LC Solution with Q-TOF LC/MS Application Note Biopharmaceuticals and Biosimilars Authors Abstract Koen Sandra, Gerd Vanhoenacker, In recent years, 2D-LC has been highly promising for the detailed characterization Mieke…

Characterizing Antibody-Drug Conjugates and Assigning Drug Conjugation Sites Using the Agilent 1290 Infinity II 2D-LC Solution Combined with the Agilent 6530 Quadrupole Time-of-Flight LC/MS System Application Note Biopharmaceuticals Authors Abstract Koen Sandra, Gerd Vanhoenacker, Antibody-drug conjugates (ADCs) are a promising…

Agilent 1290 Infinity II 2D-LC Solution Biopharmaceutical Polymer Analysis WCBP Jan 2017 Washington, DC 1 Overview • Resolving power and how to measure it • Why two-dimensional LC? • Setup of a 2D-LC System • Different modes of 2D-LC •…