Monitoring Multiple Attributes in a Single Assay Using the ACQUITY QDa Detector for Product Confirmation and Process Monitoring of Product Quality Attributes

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…

[ APPLICATION NOTEBOOK ] ACQUITY QDa Detector QC APPLICATIONS COMPENDIUM EDITION 2 Dear Colleague The 2013 introduction of the ACQUITY™ QDa™ Detector was a breakthrough in Chromatography and Mass Spectrometry integration. It was the fulfilment of a vision 20 years…

Increasing Specificity and Sensitivity in Routine Peptide Analyses Using Mass Detection with the ACQUITY QDa Detector Robert E. Birdsall and Sean M. McCarthy Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E…

Application Note Pharma & Biopharma Monitoring Product Quality Attributes of Biotherapeutics at the Peptide Level Using the Agilent InfinityLab LC/MSD XT System Authors Linfeng Wu, Lisa Zang, and Guannan Li Agilent Technologies, Inc. Abstract Single quadrupole (SQ) LC/MS has been…