Development of a High Sensitivity, Sub-Picogram SPE LC-MS Method for Quantification of Mometasone from Human Plasma

[ APPLICATION NOTE ] A Rapid Method for the Ultra-Sensitive Quantification of Fluticasone Propionate and Salmeterol Xinafoate from Human Plasma Nikunj Tanna, Lauren Mullin, and Robert Plumb Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Ultra-sensitive quantification Fluticasone propionate…

A RAPID METHOD FOR THE ULTRA-SENSITIVE QUANTIFICATION OF FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE FROM HUMAN PLASMA Authors: Nikunj Tanna, Lauren Mullin & Michael Jones Affiliations: Waters Corporation, Milford, MA, USA INTRODUCTION METHODS RESULTS DISCUSSION Fluticasone propionate (Figure 1a) (1) is…

[ APPLICATION NOTE ] UPLC-MS/MS Bioanalytical Quantification of Linaclotide from Plasma Bhaskar K, Raghu T, Taposh G, PMN Rajesh, and Dr. Padmakar Wagh India Technology Centre, Waters India pvt. Ltd, Bangalore APPLICATION BENEFITS ■■ ■■ Use of ACQUITY™ UPLC™ Columns…

Application Note Oasis™ PRiME HLB Solid Phase Extraction for High Bioanalytical Plasma Analyte Recovery and Low Matrix Effects of Top-Selling Pharmaceuticals Mary Trudeau, Margot Lee Waters Corporation Abstract The following work demonstrates a simple, generic, and broadly applicable sample preparation…