Oasis™ PRiME HLB Solid Phase Extraction for High Bioanalytical Plasma Analyte Recovery and Low Matrix Effects of Top-Selling Pharmaceuticals

Application Note Fast and Simple Bioanalytical Plasma Sample Extraction Using Oasis® PRiME HLB SPE for High Analyte Recovery Mary Trudeau, Margot Lee Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract This application…

Application Note Rapid Mixed-Mode SPE Method Development of Tyrosine Kinase Inhibitor Oncology Pharmaceuticals Oasis™ Method Development Plate Mary Trudeau, Margot Lee Waters Corporation Abstract The following work demonstrates the fast mixed-mode SPE screening approach for bioanalytical sample preparation, achieving high…

AUTOMATION OF BIOANALYTICAL SAMPLE EXTRACTION TECHNIQUES USING ANDREW+™ PIPETTING ROBOT WITH THE EXTRACTION+ CONNECTED DEVICE Jonathan P. Danaceau and Mary E. Trudeau Waters Corporation, 34 Maple Street, Milford, MA , USA INTRODUCTION AUTOMATED SAMPLE PREPARATION AND EXTRACTION Bioanalytical sample preparation…

Analysis of Plasma 17-Hydroxyprogesterone, Androstenedione, and Cortisol Using a Novel Solid-Phase Extraction (SPE) Sorbent, Oasis PRiME HLB, for UPLC-MS/MS Analysis in Clinical Research Jonathan P. Danaceau and Erin E. Chambers Waters Corporation, Milford, MA, USA A P P L I…