Combining elemental analysis and molecular techniques to characterize Ancient Egyptian mummification balms

Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 21st September 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you application notes by Agilent Technologies, LECO and Shimadzu and technical note by Thermo Fisher Scientific!<h3>1. Agilent Technologies: Automated Analysis of Foods by ICP-QQQ with Discrete Sampling and Autodilution</h3>Fast, accurate AOAC compliant food analysis using the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=9500">Agilent 9500 ICP-QQQ</a> with AVS MS and ADS 2&nbsp;<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_automated_food_analysis_9500_icp_qqq_5994_9095en_agilent_e5869385b0.pdf">Full PDF for download</a>&nbsp;</li></ul>Manufacturers and regulatory bodies, including state and federal governments, have an obligation to ensure that food is safe for human consumption. To protect public health, manufacturers and producers follow rigorous testing procedures, such as AOAC Official Method 2015.01 for the analysis of heavy metals in foods using ICP-MS.1 In recent years, global initiatives have sought to strengthen existing regulations and further reduce contaminant limits, as shown by the US Food and Drug Administration’s Closer to Zero program. Meeting these increasingly stringent targets depends on analytical instruments capable of delivering higher performance, improved sensitivity, and greater accuracy. At the same time, food testing laboratories are actively pursuing greater productivity and workflow efficiency to keep pace with evolving analytical demands.To support these goals, the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=9500">Agilent 9500 Triple Quadrupole ICP-MS</a> (ICP-QQQ) and Advanced Dilution System (ADS 2) combine seamlessly to streamline methods, improve productivity, and deliver high-quality results. Using the 9500 instrument’s unique Dual-Cell System (DCS) with Advanced Helium Mode (AHM) and Air cell mode enables effective removal of polyatomic and doubly charged interferences and enhances low-mass sensitivity.2,3 In addition, the ADS 2 simplifies sample preparation by creating calibration standards from a stock solution, pre-diluting samples before analysis, and reactively diluting any samples that exceed the calibration range. Together, these technologies support faster, more reliable delivery of accurate results.&nbsp;In this study, various standard reference materials (SRMs) were selected to represent different sample types that may be analyzed in food testing laboratories and to validate the method. As these laboratories often require high productivity, the 9500 ICP-QQQ configuration and analytical method were optimized to maximize sample throughput. The performance of the method was evaluated according to criteria set out in the AOAC 2015.01 method.<h4>Conclusion&nbsp;</h4>The Agilent 9500 ICP-QQQ with Dual-Cell System (DCS) successfully quantified a broad range of metals in diverse food matrices in accordance with an AOAC standard method. Most elements were measured in AHM, while As and Se were accurately determined at trace levels in Air cell mode using ambient air to eliminate severe doubly charged REE interferences. AHM mode effectively suppressed polyatomic interferences such as NaAr on Cu, even in samples such as NIST 1573a Tomato Leaves, where Na is present at more than 20 times the concentration of Cu.&nbsp;Together, the two DCS gas modes provided comprehensive interference control for routine food analysis, as demonstrated by recoveries of certified elements within ±25% for the food SRMs.&nbsp;Compared to single-quadrupole ICP-MS, DCS operation in both modes reduced analysis time by about 30 seconds per sample. Automation using the Agilent AVS MS discrete sampling accessory, SPS 4 autosampler, and ADS 2 autodilutor further improved productivity and delivered reliable results, including:&nbsp;<ul><li>Detection limits for As, Cd, Pb, and Hg well below the LOQs reported in AOAC 2015.01&nbsp;</li><li>Effective removal of REE2+ interferences on As and Se&nbsp;</li><li>Over 98% Lu recoveries across all SRMs, demonstrating excellent preservation of volatile elements throughout the analysis&nbsp;</li><li>Stable operation over five hours, maintaining CCV and ISTD recoveries within AOAC limits&nbsp;</li></ul>The 9500 ICP-QQQ enables high-throughput, AOAC-compliant food analysis by controlling interferences with AHM and Air cell mode, ideal for labs that need speed, reliability, and accuracy.<h3>2. LECO: Determination of Total Carbon (TC) and Total Organic Carbon (TOC) in Soil by Acid Digestion and Combustion</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/832_TC_TOC_SOIL_ACID_DIGESTION_COMBUSTION_203_821_679_e5b4978a69.pdf">Full PDF for download</a></li></ul>Total organic carbon (TOC) determination in soil is a widely used method for evaluating soil quality in agriculture. TOC levels are a key indicator of soil vitality, fertility, and capacity for atmospheric carbon sequestration. TOC represents the carbon stored in soil organic matter, which plays a vital role in supporting microbial life, enhancing nutrient availability, and improving soil structure. These benefits translate directly into better water retention, reduced erosion, and more resilient crops—key factors for regenerative systems focused on ecosystem restoration and productivity. TOC levels can also be used to monitor the effectiveness of sustainable practices like crop rotation, cover cropping, reduced tillage, and the addition of organic matter such as manure and compost. Measuring soil TOC levels helps growers optimize the use of soil amendments like compost and manure to increase organic matter without over-application.<h4>Instrument Model and Configuration&nbsp;</h4>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1883">LECO C832</a> is a carbon determinator that utilizes hightemperature combustion in a whole oxygen environment to analyze a wide range of sample types. It features a ceramic combustion furnace in a horizontal orientation designed to analyze macro sample masses. Analysis begins when a sample is weighed into a ceramic combustion boat and inserted into the furnace where combustion is initiated under a controlled flow of oxygen. After a preset time, additional oxygen is applied directly above the sample using a ceramic lance to accelerate and complete the combustion process. The gases are swept from the furnace and passed through anhydrone for the removal of moisture and are then carried to a nondispersive infrared (NDIR) cell for detection of carbon as CO2.<h4>Typical Results&nbsp;</h4>For soils containing up to 5 % carbon, a linear, force through origin calibration using LECO synthetic carbon reference materials is recommended. For soils containing more than 5 % carbon, a linear, full regression calibration using LECO synthetic carbon and calcium carbonate reference materials is recommended.<h3>3. Shimadzu: Determination of More Than 25 Nutritional, Essential and Toxic Elements in Whole Blood by ICP-MS Using Alkaline Dilution</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_05_sca_116_014_en_5fc2b521ce.pdf">Full PDF for download</a></li></ul><h5>User Benefits</h5><ul><li>Offering gas switching times &lt;5 sec and ProActive Rinsing function, short sample cycle times can be achieved&nbsp;</li><li>Using whole blood calibrators and control samples in research labs simplifies working routines&nbsp;</li><li>Alkaline media drastically improves washout capabilities for mercury and ensures proper sample stabilization compared to acidic media</li></ul>Inductively coupled plasma mass spectrometry (ICP-MS) like <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=1&amp;search=2050">Shimadzu ICPMS-2050</a> offers ultra-low detection limits and fast multi-element capability required for reliable high throughput measurement of nutritional, essential, and toxic elementsin various complex biological samples.&nbsp;While urine has been widely used to monitor elemental excretion, blood serum represents the protein-free fraction of circulating blood. Whole blood, however, contains both cellular and extracellular components, enabling a more integrated assessment of an individual’s nutritional status and exposure to potentially toxic metals than either urine or serum alone. Accordingly, whole-blood ICP-MS analysis is well suited for research applications such as nutritional assessment, toxicology, and biomonitoring studies.<h4>Conclusion</h4>The ICPMS-2050 LF was specifically configured for robust small volume analysis while reducing carry over, sample cycle times and environmental contamination impacts while being capable of successfully addressing several kind of possibly interference providing most accurate and reliable results.&nbsp;The collision- and reaction cell performs efficiently with flowrates of helium and hydrogen in low levels of 6-7mL/min. At the same time, the method uses the well established Minitorch plasma system, allowing lowest argon consumption while reducing power consumption, which makes it exceptionally cost-effective without compromising performance characteristics.&nbsp;LabSolutions ICPMS software allows to easily control the device, consumable lifetime, QC-recoveries and internal standard stability. Furthermore, features like ProActive Rinsing and Extended Rinsing speed up the method while reducing carryover risks.<h3>4. Thermo Fisher Scientific: User-defined calibrations with Niton XL5 Plus user mode</h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/user_defined_calibrations_with_niton_xl5_plus_user_mode_tn1732_en_fc054105e5.pdf">Full PDF for download</a></li></ul>The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/1992">Thermo Scientific™ Niton™ XL5 Plus Handheld XRF Analyzer</a> (shown in Figure 1) features a software function called User Mode, designed for experienced users who need to create their own calibrations.User Mode has been developed to provide maximum flexibility for performing empirical calibrations. It allows the user to specify certain parameters and to proceed with analytical method development:&nbsp;<ul><li>Define and select optimal beam conditions, including filter material and voltage*, while the current is dynamically adjusted to the maximum value.&nbsp;</li><li>Select elements and regions of interest from Na to U.&nbsp;</li><li>Select up to 12 background regions to perform background correction, background subtraction, or Compton normalization.&nbsp;</li><li>Select units of measurement for bulk concentrations, coat weight, and coating thickness.&nbsp;</li><li>Acquire normalized count rates for all selected regions of interest.&nbsp;</li><li>Construct calibration curves and apply mathematical fitting (Figure 2).&nbsp;</li><li>Manually enter calibration model equations for selected analytes as a function of element and background region intensities.&nbsp;</li><li>Validate the calibration model.&nbsp;</li><li>Analyze unknown samples.</li></ul>

News from LabRulezICPMS Library - Week 39, 2026

Acne is one of the most common skin conditions. It affects up to 85% of people during adolescence and, for many, persists into adulthood. Beyond its physical symptoms, it can also significantly affect self-confidence. Treatment often takes time, and some commonly used products can dry out or irritate the skin. Researchers at CEITEC Brno University of Technology (BUT) have developed specially modified cellulose microfibres that effectively inhibited acne-causing bacteria in laboratory tests. The fibres can be used in face masks. These findings could pave the way for new approaches to treating&nbsp;acne-prone skin.The material consists of cellulose acetate microfibres enriched with zinc oxide and subsequently treated with oxygen plasma. The zinc oxide is then gradually released into the skin, where its antibacterial action limits the growth of bacteria associated with acne. Unlike conventional products, the active ingredient is incorporated directly into the fibres and released gradually, allowing for a longer-lasting effect.“The fibres retain high efficacy without any of the additives commonly found in commercial products. The material contains exactly what is needed to combat acne effectively, with no unnecessary ingredients. Our research showed that the fibres retain their antibacterial effect for at least a year after treatment,” says Martina Říhová of the Advanced Low-Dimensional Nanomaterials research group at CEITEC BUT, who led the research. This demonstrated long-term effect opens the door to commercial applications.In the future, the same principle could also be used to treat other skin conditions complicated by bacterial infections, such as atopic dermatitis. The fibres could be incorporated not only into face masks for acne treatment but also into patches for smaller affected areas or dressings suitable for larger areas.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_K_lecbe_akne_muze_pomoci_technologie_inspirovana_vyrobou_cukrove_vaty_2_1be8944b43.jpeg" alt="CEITEC BUT/Jakub Rozboud: Technology Inspired by Cotton Candy Could Help Treat Acne: Martina Říhová from CEITEC BUT during face skin analysis." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_K_lecbe_akne_muze_pomoci_technologie_inspirovana_vyrobou_cukrove_vaty_2_1be8944b43.jpeg 235w," sizes="100vw" width="1600" height="1067"><h3>Fibres Made Much Like Cotton Candy</h3>The researchers produced the microscopic fibres using centrifugal spinning. The same physical principle is used to make cotton candy, but in this case, fine polymer fibres are formed instead of sugar strands.The breakthrough came from combining a method called Vapour Phase Infiltration, which enriched the fibres with zinc oxide, with subsequent oxygen plasma treatment. This treatment slightly disrupts the surface of the fibres, allowing the active substances to be released upon contact with water.“We were the first in the world to demonstrate this procedure using cellulose acetate fibres,” notes Martina, who has been researching acne and its treatment for seven years. She and her colleagues published their <a target="_blank" rel="noopener noreferrer" href="https://www.researchgate.net/publication/403127590_Cellulose_Acetate_Fibers_With_Infiltrated_ZnO_Nanocrystals_Activation_of_Antibacterial_Properties_Against_Acne_vulgaris_by_Oxygen_Plasma_Treatment">findings</a> in Small, one of the world’s leading scientific journals focusing on nanomaterials and nanotechnology.<h3>Researchers from Brno and Spain Joined Forces</h3>Several research teams from different institutions contributed to the material’s development. “Our team, led by Jan Macák, was responsible for preparing the fibres. We then took them to San Sebastián in Spain, to Mato Knez’s team at nanoGUNE, where they carried out the vapour phase infiltration. Next, Lenka Zajíčková’s team at CEITEC BUT treated the fibres with oxygen plasma. Finally, Zbyněk Heger’s team at the Department of Chemistry and Biochemistry at Mendel University conducted the antibacterial testing,” says Martina Říhová, describing the collaboration.The research took more than a year. Before the new material can enter routine use, it will need to undergo further biological testing, followed by clinical trials to verify its safety and effectiveness in treating patients.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CEITEC_K_lecbe_akne_muze_pomoci_technologie_inspirovana_vyrobou_cukrove_vaty_3_b21c60ae29.jpeg" alt="CEITEC BUT/Jakub Rozboud: Technology Inspired by Cotton Candy Could Help Treat Acne: Martina Říhová's microfibres developped for acne treatment." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CEITEC_K_lecbe_akne_muze_pomoci_technologie_inspirovana_vyrobou_cukrove_vaty_3_b21c60ae29.jpeg 235w," sizes="100vw" width="1600" height="1067"><blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://onlinelibrary.wiley.com/doi/10.1002/smll.202513286">Cellulose Acetate Fibers With Infiltrated ZnO Nanocrystals: Activation of Antibacterial Properties Against Acne vulgaris by Oxygen Plasma Treatment</a></h4>Martina Rihova, Denisa Fenclova, Pavan Kumar Chennam, Aniket Mukherjee, David Pavlinak, Susan Azpeitia, Kristyna Cihalova, Miloslav Pouzar, Kaushik Baishya, Lenka Zajíčková, Zbynek Heger, Mato Knez, Jan M. MacakSmall, 2026, 22, e13286<a target="_blank" rel="noopener noreferrer" href="https://onlinelibrary.wiley.com/doi/10.1002/smll.202513286">10.1002/smll.202513286</a><h6>licenced under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote><h4>Abstract</h4>In this work, we developed biodegradable cellulose acetate (CA) fibers infiltrated with ZnO nanocrystals for the Acne vulgaris (AV) treatment. The antibacterial effect (through Zn²⁺ release) was activated upon oxygen plasma treatment. CA fibers (fiber diameter ≈ 2 µm) were produced via centrifugal spinning, followed by ZnO infiltration (up to 8 wt% of Zn content) using Vapor Phase Infiltration (VPI) with varying deposition cycles. As CA fibers are naturally hydrophobic, oxygen plasma treatment was applied to turn them hydrophilic and to improve skin wetting. The combination of these steps is presented for the first time.Plasma treatment introduced oxygen‐containing functional groups on the CA surface, significantly improving wettability. Scanning electron microscopy analyses of treated fibers showed no morphological damage. Detailed characterization (using X‐ray photoelectron spectroscopy, Raman spectroscopy, energy dispersive X‐ray fluorescence, X‐ray diffraction, tranmission electron microscopy) focused on fibers with 32 and 128 VPI cycles, revealed that plasma partially oxidized and etched the surface, affecting the ZnO distribution.Plasma‐modified fibers, unlike untreated ones, exhibited antibacterial activity against AV‐causing bacteria (Cutibacterium acnes and Staphylococcus epidermidis), creating significant inhibition zones (up to 5 mm), demonstrating their potential as promising therapeutic modality. Overall, plasma treatment enabled effective surface functionalization, producing antibacterial fibers with enhanced surface properties suitable for application in AV management.

Technology Inspired by Cotton Candy Could Help Treat Acne

Article

Application

Scientific article

Science and research

Since its establishment in 2011, CEITEC has quickly developed into a cutting-edge infrastructure for research which performs highly alongside the best institutes in Europe. Among the main priorities of CEITEC are the promotion of a motivating and dynamic international scientific environment, the provision of state-of-the-art research infrastructure, and the policy of open communication and equal opportunities.

CEITEC

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Metrohm

Agilent Technologies

C&EN

SciY/Mestrelab Research

Waters Corporation

Extractables and leachables (E&amp;Ls) analysis is challenging and requires complete confidence in the results to ensure regulatory compliance. No single analytical tool can analyze all E&Ls; we offer diverse analytical technologies and expertise for the accurate identification and quantification of potential E&amp;Ls.
In this webinar our experts will discuss current regulatory updates, holistic and comprehensive analytical workflow strategies for quick scouting, profiling &amp; quantification of wide spectrum E&amp;L impurities and answer any questions you may have.
<h3>You would learn:</h3>
<ul>
<li>Regulatory updates on Extractables &amp; Leachables;</li>
<li>Overall comprehensive approach &amp; strategies to screen, detect, identify &amp; quantify Extractable &amp; Leachable compounds in various Pharma &amp; Biopharmaceutical drugs;</li>
<li>Analytical Technologies portfolio &amp; decision making software for complex studies of targeted &amp; non-targeted Extractables &amp; Leachables.</li>
</ul>
<h3>Who should attend:</h3>
<ul>
<li>Extractables &amp; Leachables analysts and laboratory managers; </li>
<li>Researchers interested in Extractables &amp; Leachables studies in Pharma/Biopharma/Medical Device/Polymer Manufacturing/CRO’s/CMO’s and others;</li>
<li>Analysts performing untargeted analyses including drug impurity profiling;</li>
<li>Quality Assurance experts in the above industries.</li>
</ul>
<blockquote>
Presenter: Antonio Chana (Product Specialist Liquid Phase Separation, Agilent Technologies)
</blockquote>
<blockquote>
Antonio Chana, Ph. D. in chemistry and Agilent product specialist in liquid phase separation for Spain and Portugal. He joined Agilent from the pharmaceutical industry where he has held positions of analytical development manager, QC manager and laboratory manager among others.
</blockquote>
<blockquote>
Presenter: Zainul Abid CKV (Product Specialist - Spectroscopy, Agilent Technologies)
</blockquote>
<blockquote>
Dr Zainul Abid is a product specialist with Agilent Technologies India Pvt Ltd based in Bangalore. He has several years of research and application development experience in Molecular spectroscopy domain. His expertise includes infrared spectroscopy and imaging, Raman spectroscopy and imaging, UV-Vis and NIR spectroscopy etc. He actively works with different industry experts to set up high-end spectroscopy laboratories.
</blockquote>
<blockquote>
Presenter: Soma Dasgupta (PhD Application Engineer, GC/GCMS, Agilent Technologies)
</blockquote>
<blockquote>
Soma received her PhD from the University of Pune, India and joined Agilent in 2016 and specializes in areas including multi-residue method development; pesticides and environmental applications and genotoxic impurities in pharmaceuticals. Prior to joining Agilent Technologies, she performed her doctorate research at the University of Pune in conjunction with the National Research Centre for Grapes where she concentrated on developing comprehensive methods for analysis of agro-chemicals in fruits and vegetables. She has worked with Thermo Fisher Scientific as Application Specialist for GC and GC-MS. Once joining Agilent, she is responsible for solutions meet our customers&#39; analytical needs. Her specialties include multi-residue method development; pesticides and environmental applications and genotoxic impurities in pharmaceuticals. She has more than 25 publications in peer-reviewed journals and application notes to her credit and a book chapter as well.
</blockquote>
<blockquote>
Presenter: Prasanth Joseph (Presales Application Engineer- LCMS, Agilent Technologies)
</blockquote>
<blockquote>
Prasanth Joseph is working as Application Engineer at Agilent Center of Excellence, Bangalore. He is having more than 16 years of experience in handling LC-MS/MS for various small molecule applications.His expertise includes MRM based screening and quantitation of various chemical residues in food commodities and pharma applications such as impurity profiling, genotoxic impurity quantitation and analysis of extractables and leachables in various packaging systems.
</blockquote>
<blockquote>
Presenter: Vinay Jain (COE Manager, Agilent Technologies)
</blockquote>
<blockquote>
Dr Vinay Jain, working as COE Manager and ICP-MS Application Scientist at Agilent Technologies India. He is Ph.D. on analytical chemistry. He has more than 30 years of analytical and research experience in spectroscopic techniques (LC-ICPMS, GC-ICPMS, ICP-MS QQQ, ICP-MS, ICP-OES, AAS, XRF, XRD) and expertise in various market segments such as Pharma, Food &amp; Farm products, Packaging, Chemical, Clinical, Environment, Petroleum, Ayurveda &amp; Herbal. His area of specialization includes new analytical method development and validation as per regulatory guidelines. He has completed more than 28 research projects with various research and regulatory organizations, of national and international importance. He is having two patents, six research paper publication; two chapters in various international handbooks and five Agilent application notes in his credit. Received TechInnovation Award in 2020 from Agilent Technologies India.
</blockquote>

Agilent Technologies: Mitigating the Risk of Extractables & Leachables Analysis - Regulatory Updates & Analytical Workflow Strategies

Mitigating the Risk of Extractables & Leachables Analysis - Regulatory Updates & Analytical Workflow Strategies

Do you think time-consuming tasks in ICP-MS are inevitable? Something that has to be accepted as part of routine operations? Find out how ICP-MS 7850 helps you easily meet your analytical requirements while simplifying laboratory workflow and improving performance and satisfaction for analysts and laboratory managers.
The intelligence embedded in the ICP-MS 7850 provides a more efficient way to perform metal analysis by reducing unnecessary wasted time so that your staff can focus on activities that generate greater value for the laboratory.
<h5>WHAT YOU WILL LEARN:</h5>
<ul>
<li>Simplify the preparation of your samples and standards</li>
<li>Facilitate the implementation of analytical methods and the handling of the instrument</li>
<li>Improve confidence in your results whatever the matrix analyzed</li>
<li>Maintenance operations and reduce instrument downtime</li>
<li>Optimize and obtain better instrument and samples’ insights</li>
</ul>
<blockquote>
Presenter: Dr. Raimund Wahlen (Product Specialist, Agilent Technologies, Inc., USA)
</blockquote>

Agilent Technologies: The new Agilent 7850 ICP-MS - Free your workflows from common time traps 

The new Agilent 7850 ICP-MS - Free your workflows from common time traps 

The smarter way to avoid time traps in your laboratory.

Agilent 7850 ICP-MS - Free your workflows from time traps 

Watch this on-demand webinar to learn more about the advantages of NIRS: Receive multiple parameters (e.g., moisture, viscosity, hydroxyl value) in less than one minute and reduce costs of your QC lab up to 90%!

Reduce costs in QC labs

Learn more about the advantages of NIRS: Receive multiple parameters (e.g., moisture, viscosity, hydroxyl value).

After two introductory webinars to the tool presented by our colleague Dr. Gary Sharman, we wanted to continue this Mnova Gears webinar series by sharing more in-depth use cases. Different users from big and small Pharmas and Universities will be telling us how they have automated their analytical data workflows using Mnova Gears.
<h3>ABSTRACT</h3>
To streamline the workflow of the analytical data processing, data reporting and management of registered compounds in our SMDI database, we have collaborated with Mestrelab Research over the past two years to build an efficient and automated workflow using Mgears and other Mnova software. In this new workflow, the 1D/2D NMR and LCMS raw data from multiple instruments (Bruker, Agilent, and Thermo) are detected in real-time and paired with the expected chemical structure.
Next, the NMR data are processed and analyzed (FT transform, phase/baseline correction, peak picking and multiplet analysis etc.), and together with the LCMS data, the proposed structure is verified by comparing the expected molecular ion and isotope pattern, the predicted NMR spectra and peak assignments.
The results are reported in one document in a predefined format for both NMR and LCMS. Then, the reports are saved to a Mnova DB and Genentech SMDI database.
This process happens in real-time without human intervention. Currently the system is running constantly 24/7 serving users who have access to the SMDI database. All users can easily retrieve the reports from SMDI data browser or by searching the Mnova DB. After user reviewing and revising in Mnova, the reports can be saved back to the databases.
<h5>What to expect</h5>
A demonstration of how Mnova Gears was set up and run at Genentech’s labs.
<h5>Key points</h5>
<ul>
<li>Mnova Gears effectively streamlines the workflow of analytical data processing and reporting</li>
<li>Mnova Gears creates “live” and interactive analytical data reports in SMDI, Genentech’s database</li>
<li>“Live” analytical data reports stored in Mnova DB make retrieving old analytical data for review and publication much easier</li>
</ul>
<h5>Who should attend?</h5>
Scientists in pharma, biotech and other fields who want to automate NMR and LCMS data processing and reporting.
<blockquote>
Presenter: Yanzhou Liu (Scientific Manager, Genentech)
</blockquote>
<blockquote>
I have been working in pharmaceutical industry as a medicinal chemist and NMR spectroscopist for more than 20 years. Currently, I manage the NMR facilities in Discovery Chemistry Department at Genentech.
</blockquote>

Mestrelab Research: Using Mnova Gears to Automatically Process and Report NMR & LC/MS Data in Real-Time at Genentech

Using Mnova Gears to Automatically Process and Report NMR & LC/MS Data in Real-Time at Genentech

Automated real-time processing of NMR & LC/MS using Mnova Gears at Genentech.

Using Mnova Gears to Automatically Process and Report Data

Are you an analyst, manager, or reviewer who follows the social distancing guidelines but need to get work done without full access to your lab? Especially important today, Remote Access is a key feature that can increase productivity, reduce compliance costs and can be an integral part of a disaster recovery plan.
This virtual seminar introduces options using &quot;Thin Client technology which enables all Masshunter, ChemStation or OpenLab CDS products to be accessed outside the lab, whether this is at from nearby desks, across sites, or from home. 
<h3>Key Learning Objectives</h3>
<ul>
<li>See how OpenLab can help laboratory analysts increase productivity, work more efficiently as well as reduce compliance costs.</li>
<li>See how OpenLab can help laboratories reduce implementation/upgrade times and clear out bench space by reducing the need for in-lab computers.</li>
<li>See how Analysts continue to do their work even when physical access to the laboratories is restricted or very limited.</li>
</ul>
<h3>Who Should Attend</h3>
<ul>
<li>Lab Managers/Supervisors</li>
<li>IT professionals</li>
<li>Laboratory Analysts</li>
</ul>
<blockquote>
Presenter: Mike Ratto (Informatics Application Specialist, Agilent Technologies)
</blockquote>
<blockquote>
Presenter: Alexandra Taylor (Associate Editor, C&amp;EN)
</blockquote>

C&EN: Agilent OpenLab Remote Access Solutions to increase productivity

Agilent OpenLab Remote Access Solutions to increase productivity

The pharma industry is undergoing constant evolution, requiring implementation of more efficient process while experiencing more stringent regulatory requirements.
The ability to be fast to market, while maintaining a strong understanding of your product, is critical.
At Agilent, we understand your analytical requirements.
<h3>Thursday, 18th February - Live Broadcast</h3>
<h5>1. 10:15 a.m. – 11:15 a.m. CET The fundamentals of dissolution</h5>
<blockquote>
Presenter: Owain McKenzie (EMEA Dissolution Business Team Manager, Agilent Technologies)
</blockquote>
<h5>2. 12:00 p.m. – 01:00 p.m. CET Minimize Regulatory Risk by moving to a Customized Instrument Qualification Solution</h5>
<blockquote>
Presenter: Garry Wright (European Laboratory Compliance Specialist, Agilent Technologies)
</blockquote>
<h5>3. 03:00 p.m. – 04:00 p.m. CET Dissolution best practices and qualification</h5>
<blockquote>
Presenter: Owain McKenzie (EMEA Dissolution Business Team Manager, Agilent Technologies)
</blockquote>

Agilent Technologies: Agilent 1st Pharma Virtual Symposium

Agilent Pharma Virtual Symposium - Day 2

Manage Entire Workflows and Your Entire Lab. Join us to explore Agilent SLIMS, the perfect fit for your laboratory processes.
SLIMS combines the best of a laboratory information management system (LIMS) and an electronic laboratory notebook (ELN) to enable end-to-end solutions and manage all content and all context in the laboratory. SLIMS is an ideal complement to Agilent software. It integrates with simple and complex instruments and supports workflows for Analytical, NGS, Biobanks, and R&amp;D labs. It is flexible and configurable, helping you increase your lab’s productivity.
<h3>Key Learning Objectives:</h3>
<ul>
<li>Introduce the Agilent SLIMS Lab Workflow Platform. </li>
<li>Each session will be focused on a different application i.e. Analytical, NGS, and Biobanks.</li>
<li>See how SLIMS can interact with the rest of the Lab and enables a digital lab</li>
<li>Discover how Agilent workflow solutions enable an end-to-end solution that can manage all lab content, context, and results</li>
</ul>
<h3>Who Should Attend:</h3>
<ul>
<li>Lab Managers</li>
<li>Quality Managers</li>
<li>IT Managers</li>
</ul>
<blockquote>
Presenter: Karim Saied (SLIMS Field Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Karim recently joined Agilent Technologies in 2019 as a Field Application Engineer. Holding a Bachelor’s degree in Biology, he graduated in 2019 from the University of Lausanne with a Master’s degree in Molecular Life Sciences with a specialization in bioinformatics. Passionate about the business side also, he joined the SLIMS Enterprise Pre-Sales Team.
</blockquote>

Agilent Technologies: Analytical Labs: SLIMS Introductory Demonstration

Analytical Labs: SLIMS Introductory Demonstration

We are pleased to invite you to the 1st Agilent Lab Informatics Virtual Summit.
During the course of our summit, there will be talks from Agilent experts, live interactive Q&amp;A, software demonstrations as well as a virtual exhibition.
Stay up to date with the latest trends and developments in Laboratory Informatics!
<h3>Topics include:</h3>
<ul>
<li>An Ecosystem for a Digital Lab – Aspects and Possibilities</li>
<li>Cloud Solutions</li>
<li>Data Integrity</li>
<li>Laboratory Information Management System (Agilent SLIMS)</li>
<li>Chromatography Software</li>
<li>Scientific Data Management Systems</li>
<li>Computer System Validation</li>
</ul>
Keep your knowledge about the evolving landscape of scientific software up to date. Whether you are planning to introduce a new system in your lab soon, or you are currently happy with your system, you will learn something important and will be much better informed after visiting this exciting event.
We will have an exhibition where you can visit various booths to learn more about our latest products and solutions. Our booth team will be there for you virtually from 08:00 a.m. – 05:00 p.m. CET; to answer any questions through a convenient chat-box option or via a private video chat.

Agilent Technologies: 1st Agilent Lab Informatics Virtual Summit

1st Agilent Lab Informatics Virtual Summit

From the everyday consumer to scientists in the laboratory, we all rely on accurate information to make critical decisions.
Waters Corporation is pleased to bring together chromatography thought leaders for a week of scientific talks, live demonstrations, panel discussions, and networking regarding novel liquid chromatography technologies and applications.
Join us for this virtual symposium beginning with a plenary session on Monday, March 22nd and followed by application sessions for Pharma, Food, Materials and Biomedical Research throughout the week!
<h3>THURSDAY, MARCH 25, 2021</h3>
<h3>Morning Session - 5:00 - 6:30pm CET</h3>
<h4>Accelerating Materials Innovation with Modern Separations Technologies</h4>
Intense pressures from consumers and regulatory bodies for safer, more sustainable, and higher-performing materials require precise analytical and measurement tools that help secure a first-to-market advantage and adhere to critical regulations by providing deep insights into polymer specimen quickly, efficiently, and with a high degree of reliability. This session will provide a series of talks on polymer separation techniques and capabilities.
<h4>Presentations:</h4>
<h5>1. Welcome/Introduction (Bryan Katzenmeyer, Ph.D., Waters Corporation)</h5>
<blockquote>
Presenter: Bryan Katzenmeyer, Ph.D. (Senior Manager, Materials Science, Waters Corporation)
</blockquote>
<blockquote>
Bryan Katzenmeyer has over 10+ years of experience specializing in mass spectrometry and separation techniques for the characterization of materials, polymers, monomers, and small molecules as well as increasing leadership roles within technical organizations. He currently oversees the Americas Materials Science business marketing segment for Waters Corporation. The Materials Science business market focuses on polymers, fine and specialty chemicals, extractables/leachables, medical device testing, cosmetics and personal care products, fuel/energy, and agrochemicals. Prior to joining Waters, Bryan was an Analytical Group Leader and Senior Scientist at Valspar (now part of Sherwin-Williams). While here he managed the liquid chromatography and mass spectrometry team focused on developing and validating analytical methodologies to characterize extractables and leachables, resins, oligomers, monomers, and other small molecules in packaging coatings for the food and beverage industries. Bryan received his Ph.D. in Polymer-Analytical Chemistry at The University of Akron working under Distinguished Professor Chrys Wesdemiotis. Here, he researched interfacing liquid chromatography and ion mobility separation with multi-dimensional mass spectrometry for the structural characterization of polymeric materials. He also obtained a M.S. in Chemistry from the University of Wisconsin-Madison and a B.S. in Chemistry from Penn State University. 
</blockquote>
<h5>2. Multi-Detector Size Exclusion Chromatography: Accelerating Innovation Through Greater Insight Into Polmer Performance Properties</h5>
<blockquote>
Presenter: Amandaa Brewer, Ph.D. (Senior Research Scientist, Arkema)
</blockquote>
<blockquote>
Amandaa K. Brewer received her Ph.D. in Analytical Chemistry in 2010 from Florida State University (FSU) and her B.S. in Chemistry from Roanoke College in 2005. Her Ph.D. thesis was under Andre Striegel and titled “Multi-Detector Hydrodynamic Chromatography: Particle Characterization and Ultra-High Molar Mass Polymer Analysis.” From 2011 to 2015 she worked at Tosoh Bioscience LLC, where she was first the GPC Technical Specialist and later advanced to the GPC Sales Support Leader. In May 2015 Amandaa joined Arkema Inc., at their North America Research and Development site in King of Prussia, Pennsylvania. She is currently a Senior Research Scientist in the Analytical and Systems Research Group at Arkema and heads the Gel Permeation Chromatography Laboratory. Her research interests are in the area of macromolecular characterization, in particular in using structure-property relationships obtained by multi-detector size-based separations techniques to aid in the understanding of end-product performance and applications as well as the characterization of ultra-high molar mass polymers and applying multi-detector hydrodynamic chromatography to industrial applications. Amandaa is the author of peer-reviewed publications focusing in the area of size based separation methods such as size-exclusion and hydrodynamic chromatography coupled to multi detection methods, namely multi-angle light scattering, quasi-elastic light scattering, differential viscometry, and differential refractometry. She has also published an encyclopedia article on gel-permeation column packing material and lectured in the area of multi-detector size-exclusion chromatography.
</blockquote>
<h5>3. Expanding Detection Capabilities in SEC and APC: On-line SEC-ICP/MS and APC-ICP/MS Hyphenation</h5>
<blockquote>
Presenter: Miroslav Janco, Ph.D. (Senior Research Scientist, Dow)
</blockquote>
<blockquote>
Dr. Miroslav Janco is a senior research scientist and a Polymer Separations GTN leader within the Analytical Science team of the Core R&amp;D organization at Dow Chemical. He holds a M.S. with honors in Chemical Engineering from the Institute of Fine Chemical Technology in Moscow, Russia and a Ph.D. in Macromolecular Chemistry from the Polymer Institute of the Slovak Academy of Sciences in Bratislava. His extensive career in the field of separation science and analytical chemistry was built in renowned laboratories around the word including Osaka University (Japan), University of California—Berkeley, Hahn-Meitner Institute (Berlin, Germany), and the University of Torino (Italy) where he developed a unique LC CAP-NMR hyphenated technique for the separation of polymers by tacticity, fast polymer separations by HPLC on monolithic columns and applied LC CAP for separations of block copolymers, respectively. Currently, his research is focused on the separation and characterization of polymers on both particle and molecular levels by HDC and LC, including SEC, HPLC, LC CAP modes using conventional (RI, UV, ELSD) and enhanced (LS, VIS, ICP/MS, MALDI and NMR) detections as well as coupled (2D-LC) and hyphenated (LC-ICP/MS and LC-NMR) techniques. Dr. Janco has authored or coauthored 26 original scientific papers in peer-reviewed journals and presented his research at more than 60 international conferences. His latest contribution to the field of polymer separation and characterization is development of Ultra-High Pressure Size Exclusion Chromatography (UHP SEC) commercialized as Advanced Polymer Chromatography (APC) by Waters.
</blockquote>
<h5>4. Recycling Gradients in Polymer Chromatography, A New Approach in HPLC on Polymers? (Bastiaan Staal, Ph.D., BASF)</h5>
<blockquote>
Presenter: Bastiaan Staal, Ph.D. (Head of Laboratory, BASF)
</blockquote>
<blockquote>
Dr. Bastiaan Staal is a polymer chemist who finished his Ph.D. in 2005 in the University of Eindhoven (the Netherlands) on copolymer characterization by MALDI-TOF-MS. Since 2006 he is a lab leader at BASF, responsible for GPC and HPLC of polymers for the central research at BASF. His main interests include developing alternative methods in data processing for both HPLC and GPC (mainly handling nonlinear detectors), searching for stable conditions for performing proper GPC, unraveling (MALDI) MS data of co-polymers and hyphenation techniques like GPC-IR, and pushing 2D chromatography (HPLCxGPC) to its limits. His main drive is forming the bridge between theory and the industrial praxis.
</blockquote>
<h3>Afternoon Session - 7:30 - 9:00pm CET</h3>
<h4>LC Method Migration - Will my Validated Method Work on this New LC Sytem?</h4>
Concerned about your validated LC method working on the new instrument? Excited about getting even more out of your method with newer LC systems? This session will introduce a process to identify and mitigate risk due to instrument performance when switching methods to upgraded or new instruments. The session will also address how to scale LC methods.
<h4>Presentations:</h4>
<h5>1. Mitigating Risk While Upgrading LC Assets in the Regulated Laboratory using Quality by Design</h5>
<blockquote>
Presenter: Pauline McGregor, Ph.D. (CChem MRSC, PMcG Consulting)
</blockquote>
<blockquote>
Pauline McGregor Ph.D. CChem MRSC founded PMcG Consulting in September 2006. She has over thirty years’ experience in the Pharmaceutical industry and holds a PhD in organic, analytical chemistry . She originally came to Canada from Edinburgh, Scotland in 1995 to carry out her postdoctoral studies at the University of Western Ontario. Pauline brings a technical expertise to laboratories which enable her to assist them to develop, transfer, verify and validate analytical procedures, and also optimize efficiency with regards to laboratory operations and troubleshooting in an analytical development and QC environment. She been involved in the development and evolution of lifecycle management for analytical procedures and AQbD since 2010. Pauline was a member of the USP expert panel for Validation, Verification and Transfer of Analytical Procedures and a member of a USP Chemical Medicines expert review committee. She continues to be a USP volunteer Expert Advisor and is a Member of the Royal Society of Chemistry , UK. 
</blockquote>
<h5>2. Instrument Suitability Evaluation of HPLC Systems for a USP Organic Impurities (Paula Hong, Ph.D., Waters Corporation)</h5>
<blockquote>
Presenter: Paula Hong, Ph.D. (Principal Consulting Scientist, Waters Corporation)
</blockquote>
<blockquote>
Paula Hong is a Principal Consulting Scientist at Waters Corporation in the Systems Design and Development Application Laboratory. She received her Ph.D. in Inorganic Chemistry from The University of Pennsylvania (Philadelphia, PA), focusing on the reactivity of transition metal/silane complexes. Paula has over 15 years’ experience in the area of LC and LC/MS applications, including amino acid analysis, ion-exchange and peptide mapping. She began her career at Waters in the chemistry division focusing on novel column chemistries for biopharmaceutical applications, including studies on the first hybrid sub 2-µm SEC column. Her more recent work has focused on understanding the role of instrumentation characteristics on chromatographic separations. These studies have included method development for both reversed-phase and supercritical fluid applications as well as method transfer. She has authored over 25 journal articles, white papers, and application notes on a variety of chromatographic principles. 
</blockquote>
<h5>3. Migration of Chromatographic Procedures (Oscar Quattrocchi, D’Amico Sistemas and US Pharmacopeia)</h5>
<blockquote>
Presenter: Oscar Quattrocchi (Training Manager, D’Amico Sistemas and US Pharmacopeia)
</blockquote>
<blockquote>
Oscar Quattrocchi is currently Training Manager at D´Amico Sistemas S.A. since 2008 and a member of the USP General Chapters Expert Committee, Chemical Analysis since 2005, now in the fourth cycle finishing in 2025, former Vicechair of the USP GCEC, former Chair of the USP Residual Solvents Expert Panel, former Vicechair of the USP Medicines Compendium and currently Chair of the USP Spanish Translation Expert Panel. He had worked more than 30 years in the Pharmaceutical Industry as Manager for Analytical Development, Stability Testing and international registration of Drug Substances and Drug Products. He published two books on HPLC and several articles in scientific publications and was a speaker in numerous congresses and symposiums in Argentina, Brazil, and the USA.
</blockquote>
<h5>4. Panel Discussion (Moderated by: Isabelle VuTrieu, Adriana Tirado, Waters Corporation)</h5>
<blockquote>
Moderated by: Adriana Tirado (Market Development Specialist, Mexico &amp; LAD, Waters Corporation)
</blockquote>
<blockquote>
Adriana is the Market Development Specialist in the Spanish-speaking countries of Latin America at Waters and has 15 years of experience in Sales &amp; business development. She joined Waters in 2012 as a sales representative for northern Mexico. She has worked in different companies as a sales executive developing brand presence in the analytical &amp; Life Sciences markets, where she also held the position of service engineer and technical support engineer in liquid chromatography. Prior to that, she was an Associate professor in the Autonomous University of Nuevo León working in the analytical area and supporting the natural products research line of the analytical department in the Faculty of Medicine. She studied Clinical Chemistry Biologist and has a master’s degree in Biomedical Chemistry from the Autonomous University of Nuevo León.
</blockquote>

Waters LC Symposium - Materials and Pharma

More and more companies are choosing to look toward financing options as opposed to capital expenditure to fund their laboratory purchases. We discuss the benefits of this approach.​
<blockquote>
Presenter: Richard Styles (Director of Leasing EMEAI, Waters)
</blockquote>
<blockquote>
Richard has been with Waters for 5 years developing innovative, tailor made finance solutions for our customers. He has over 30 years of domestic and international experience through management roles at bank based and manufacturer captive leasing companies.​
</blockquote>