<p><strong>Dear friends and fans of mass spectrometry,</strong></p>
<p><strong>The history of a method for studying of matter known as mass spectrometry dates back more than a century. The foundations have mostly been laid by physics studying discharges in gases. After about five decades mass spectrometry entered the domain of chemistry and evolved into an excellent tool for studying the structure of chemical compounds. Recently we are witnessing its expansion into the field of cellular, molecular, and structural biology. The technology of mass spectrometry developed immensely over the time. Let us take a tour into the history and learn about the past technologies. Let us explore the state-of-art mass spectrometry.</strong></p>
<p>A technical museum focused on unique and significant part of science, the Czech Museum of Mass Spectrometry will display and explain laboratory instrumentation that encompasses physics, chemistry, engineering and informatics and combines them into a device that contributes to many parts of our daily life.</p>
<p>Czech and English speaking visitors will have an opportunity to learn about the principles and applications of mass spectrometry, its history, and important scientists including Nobel price winners, while experiencing a remarkable collection of mass spectrometers. Founded by mass spectrometry enthusiasts Jaroslav Pol (Thermo Scientific) and Josef Cvacka (Institute of Organic Chemistry and Biochemistry) and sponsored by Frantisek Turecek (University of Washington, Seattle), the Czech Museum of Mass Spectrometry is now being assembled and will open in Prague in 2017. Donations of mass spectrometry artifacts are gratefully appreciated; those willing to contribute please contact the curators.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/d3e7627196634c0a8fa129f95fef6edd/obrazek.png" alt="The Czech Museum of Mass Spectrometry"/></p>
<h3><strong>Mass spectrometry</strong></h3>
<p>Study of matter through the formation of gas-phase ions that are characterized using mass spectrometers by their mass, charge, structure, and/or physico-chemical properties.</p>
<h3><strong>Mass Analyzers</strong></h3>
<h5><strong>Fourier Transform Ion Cyclotron Resonance</strong></h5>
<p>Mass spectrometer based on the principle of ion cyclotron resonance in which an ion in a magnetic field moves in a circular orbit at the cyclotron frequency that is characteristic of its m/z value. Ions are coherently excited to a larger radius orbit using a pulse of radio frequency electric field, and their image charge is detected on receiver plates as a time domain signal. Fourier transformation of the time domain signal results in a frequency domain signal that is converted to a mass spectrum based on the inverse relationship between cyclotron frequency and m/z.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/1628c6d87adf47538f70c2d7ce971db9/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Ion Trap</strong></h5>
<p>Device for spatially confining ions using electric and magnetic fields alone or in combination.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/bcc0887a778f4df29f488bcd87ce8718/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Linear Ion Trap</strong></h5>
<p>Two-dimensional Paul ion trap in which ions are confined in the axial dimension by means of a static electric potential.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/6d35a6cdb4ee4baa95ad2d831b20db19/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Orbitrap</strong></h5>
<p>Ion trapping device that consists of an outer barrel-like electrode and a coaxial inner spindle-like elec- trode that form an electrostatic </p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/4c8de0a71fef446fa44829e9d37c8b62/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Sector</strong></h5>
<p>Device that produces a magnetic field perpendicular to a charged particle beam that deflects the beam to an extent that is proportional to the ratio of particle momentum and charge.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/240ae6e09cb443508bf7dce8309b2928/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Time of Flight</strong></h5>
<p>Mass spectrometer that separates ions by m/z in a field-free region after acceleration through a fixed accelerating potential. Ions of the same initial translational energy and different m/z require different times to traverse a given distance in the field-free region.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/0d0eaa3a8aa544d1abcca833a9e6e9ae/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Triple Quadrupole</strong></h5>
<p>Tandem mass spectrometer comprising two transmission quadrupole mass spectrometers in series, with a (non-selecting) RF-only quadrupole (or other multipole) between them to act as a collision cell.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/b6e4bd36ccb44cd8a93e84353b28a357/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h3><strong>Ion Sources</strong></h3>
<h5><strong>Atmospheric pressure chemical ionization</strong></h5>
<p>Atmospheric pressure chemical ionization (APCI) is chemical ionization of a sample that is a gas or nebulized liquid, using an atmospheric pressure corona discharge or beta emitter such as 63Ni.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/d562c1ce1a9f43c78d8a93a2c6c43932/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Atmospheric pressure photoionization</strong></h5>
<p>Atmospheric pressure photoionization (APPI) is direct ionization of molecules at atmospheric pressure by electron detachment induced by photons forming M+•, or atmospheric pressure chemical ionization in which the reactant ions are generated by photoionization of suitable dopant species and subsequent ion/molecule reactions of their molecular ions.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/828a17ec377a4313bdd59f9275192e87/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Desorption electrospray ionization</strong></h5>
<p>Desorption electrospray ionization (DESI) is formation of gas-phase ions from a solid or liquid sample at atmospheric pressure through the inter- action of electrosprayed droplets with the sample surface.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/86624af57b96403586bd27b3bafccec3/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Electrospray ionization</strong></h5>
<p>Electrospray ionization (ESI) is spray ionization process in which either cations or anions in solution are transferred to the gas phase via formation and desolvation at atmospheric pressure of a stream of highly charged droplets that result from applying a potential difference between the tip of the electrospray needle containing the solution and a counter electrode.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/673ec39a73b64561805cf60670486635/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Fast atom bombardment ionization</strong></h5>
<p>Fast atom bombardment ionization (FAB) is ionization of molecules initiated by a beam of neutral atoms with translational energies in the keV range. Labile molecules susceptible to dissociation are dissolved in an involatile liquid matrix that absorbs the energy of the bombarding atoms to form a selvedge region above the liquid surface in which ionization of the molecules occurs.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/afda171085f54f6e856bc930cf873fca/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Matrix-assisted laser desorption/ionization</strong></h5>
<p>Matrix-assisted laser desorption/ionization (MALDI) is formation of gas-phase ions from molecules present in a solid or liquid matrix that is irradiated with a laser. The matrix is a material that absorbs the laser energy and promotes ionization.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/39f899169e27496f938621f0d25a0f12/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>
<h5><strong>Secondary ion mass spectrometry</strong></h5>
<p>Secondary ion mass spectrometry (SIMS) is technique in which a focused beam of primary ions produces secondary ions by sputtering from a solid surface. The secondary ions are analyzed by mass spectrometry.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/fd584fd784ab4c5197b461de5c42c5ee/obrazek.png" alt="The Czech Museum of Mass Spectrometry/Martin Strohalm"/></p>


The Czech Museum of Mass Spectrometry

<p><strong>The origins of mass spectrometry in Czechia date back to the 1950s when a group of young scientists in the newly founded Czechoslovak Academy of Sciences started to build the first mass spectrometer in the country. Over the years, mass spectrometry gradually developed and gained in importance. The conference will explore the history, status and perspectives of mass spectrometry. It will mark the opening of the Czech Mass Spectrometry Museum and contribute to celebrations of 70th anniversary of mass spectrometry in our region.</strong></p>
<h3><strong>Organizing institutions</strong></h3>
<p><a href="https://gcms.cz/companies/22">ÚOCHB/IOCB PRAGUE</a></p>
<p><a href="https://gcms.cz/companies/21">Czech Society for Mass Spectrometry/Česká společnost pro hmotnostní spektrometrii</a></p>
<p><a href="https://gcms.cz/companies/7">Ioannes Marcus Marci Spectroscopic Society/Spektroskopická společnost Jana Marka Marci</a></p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/03cce7b42575402eb5c91750579dec76/obrazek.png" alt="ÚOCHB/IOCB PRAGUE - Czech Society for Mass Spectrometry/Česká společnost pro hmotnostní spektrometrii -  Ioannes Marcus Marci Spectroscopic Society/Spektroskopická společnost Jana Marka Marci"/></p>
<h3><strong>Conference program</strong></h3>
<p>Available on <a href="http://ms-prague2020.uochb.cas.cz/program.php">Prague Meeting on Historical Perspectives of Mass Spectrometry website</a></p>
<h3><strong>Venue</strong></h3>
<p>The conference will take place in three localities in Prague districts Dejvice and Bubeneč: National Library of Technology (lectures), Institute of Organic Chemistry and Biochemistry of the CAS (vernissage tours), and Old Wastewater Treatment Plant (poster session &amp; dinner).</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/0827c374acec4191b3ff1610c02ae928/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Prague Meeting on Historical Perspectives of Mass Spectrometry"/></p>
<h3><strong>Czech Museum of Mass Spectrometry</strong></h3>
<p>The museum aims to collect and display artifacts related to mass spectrometry, especially those associated with our geographical region. The technical museum shows key components of mass spectrometers used in the past and in contemporary laboratory practice, and it also displays historical documents, photographs, books, etc. The museum&#39;s mission is expressed in two words: education and inspiration. It demonstrates technologies hidden behind the cover and inside the vacuum systems, thus allowing a better understanding how the mass spectrometers actually work. Displayed technical solutions, prototypes, ideas, and stories can be inspiring for students, scientists, and designers of instruments.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/8619b6eab01a4ec18b531bf1a7d20dff/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry"/></p>
<h3><strong>Exhibition</strong></h3>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/3bc183e590444d81a74ce5538a9b5b59/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry"/></p>
<h3><strong>Website</strong></h3>
<p>The <a href="http://www.ms-museum.org/">website</a> will store the museum database with a detailed description of exhibits and bring topics from MS history.</p>
<p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/c4771b1119d84181929ea3cd97c56e76/obrazek.png" alt="ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry"/></p>
<h3><strong>Donations</strong></h3>
<p>The Czech Museum of Mass Spectrometry welcomes donations to its collection: instruments or their parts (broken, damaged, unused), and documents, photographs or books related to MS history. </p>


Prague Meeting on Historical Perspectives of Mass Spectrometry and  the Czech Mass Spectrometry Museum

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The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) is a leading scientific institution in the Czech Republic, recognized internationally. Its primary mission is basic research in the fields of chemical biology and medicinal chemistry, organic and material oriented chemistry, chemistry of natural compounds, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. 

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Prague Meeting on Historical Perspectives of Mass Spectrometry and the Czech Mass Spectrometry Museum