Quantitative NMR (qNMR) Workflow Automation with ACP 2.0 – Practical Session 2

Quantitative NMR (qNMR) workflow automation with ACP 2.0 – Practical Sessions | Bruker

Session 2 – Advanced is part of 2-part webinar series is designed to provide hands-on guidance on how to set up quantitative NMR (qNMR) workflows with Advanced Chemical Profiling 2.0 (ACP 2.0).

Builds on the first practical session and demonstrates how to handle similar analytical questions but with more complex datasets necessitating advanced fitting strategies including simultaneous fitting of overlapping signals and baseline handling, as well as customized calculations to process and express results. Additionally, the setup of external calibrations will be explained.

Registration required for each session.

What to Expect from this Practical Session

In these hands-on sessions, you will learn…

• … how to create (automated) analysis methods for the most common qNMR workflows including but not limited to
  • Purity assay analysis
  • Concentration analysis   
  • Relative quantification
• … how to analyze hundreds of datasets in one go   
• … how to have your data analyzed on-the-fly (from sample to report)

By the end of this series, you will be able to apply the steps demonstrated and analyze your own datasets – whether simple or complex – quantitatively with ACP 2.0.

Learning by Doing

You will be provided with the spectra used as part of the practical session allowing you to click-along and create the shown methods yourself!

About Advanced Chemical Profiling 2.0

ACP 2.0 software empowers laboratories to implement push‑button, end‑to‑end automated NMR workflows across the entire product lifecycle, from early research through development and manufacturing. It redefines how analytical and testing facilities can leverage NMR technology by enabling harmonized workflows, significantly improving operational efficiency, and reducing costs through standardized, GMP‑ready, operator‑independent analysis, seamlessly connecting sample to final reporting.
 

Speaker: Dr. Valentin Poirier (Senior Solution Developer Biopharma & Applied Division, Bruker BioSpin)

Valentin joined Bruker BioSpin in 2024 as a Solution Product Manager in the BioPharma team. In this role, he collaborates with the pharmaceutical industry to advance Nuclear Magnetic Resonance solutions tailored to drug development and manufacturing, with a strong emphasis on quality control and compliance. A trained chemist, he entered the pharmaceutical industry after completing his Ph.D. Over the past decade, he has managed analytical platforms at CROs (Albhades and Evotec), focusing on NMR and Mass Spectrometry as modern tools for analytical sciences and regulated applications (GMP/GLP). As a technical expert, he has contributed to the development of dozens of analytical projects for pharmaceutical applications and quality control, with a customer-centric and problem-solving approach.

Speaker: Dr. Kyle Rodriguez (NMR Application Scientist, Bruker)

Dr. Kyle Rodriguez received his PhD in Chemistry from the University of New Hampshire in 2017, and then held a post-doc position at the Adolphe Merkle Institute in Fribourg, Switzerland. In 2020, he joined a collaboration between the Swiss Federal Institute of Technology Lausanne (EPFL) and the start-up, Annaida Technologies S.A. as an Applications Scientist through an Innosuisse grant. Kyle joined the America’s applications team as an NMR Applications Scientist at Bruker in 2021, where he helps scientists reach their research goals through innovative NMR solutions.