Mastering HILIC Chromatography: from Principles to Best Practice

Th, 1.10.2026 10:00 CEST
Join the Phenomenex webinar on HILIC chromatography. Learn retention mechanisms and method development for polar compound analysis.
Phenomenex: Mastering HILIC Chromatography: from Principles to Best Practice
Phenomenex: Mastering HILIC Chromatography: from Principles to Best Practice

This webinar provides a practical introduction to HILIC chromatography, focusing on retention mechanisms, stationary phase selection, mobile phase optimization, and method development strategies. Best practices for LC-MS applications, column care, and routine operation will also be discussed to help improve method robustness, reproducibility, and overall analytical results. 

Key Learning Points
  • Introduction to HILIC: when and why to use HILIC
  • Impact of stationary phase chemistry
  • Method development scheme
  • Column care & best practices
Who Should Attend
  • This webinar is intended for analysts, researchers, and laboratory professionals working with HPLC and LC-MS in environmental, pharmaceutical, food, and quality control laboratories who are interested in developing, optimizing, and troubleshooting HILIC methods for polar compounds.

Presenter: Luigi Margarucci (EMEA Seminar & Application Lead, Phenomenex)

Luigi holds a PhD in Pharmaceutical Sciences and began his career at Phenomenex in 2015 as a Technical Sales Consultant. In 2017, he took on the role of Mass Spectrometry Specialist, followed by Chromatography Training Manager in 2020. Since 2021, he has served as Technical Manager for Italy.

He gained extensive experience in chromatography coupled with mass spectrometry while working as a researcher and research fellow at the University of Salerno, collaborating with leading chromatography and mass spectrometry centers in Italy and across Europe, including Utrecht University (The Netherlands).

To date, Luigi has authored 27 scientific publications and has written and delivered numerous seminars on analytical techniques such as HPLC, GC, and SPE. 

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