Assessing biotherapeutic stability through forced degradation using intact and subunit icIEF-UV/MS workflows

RECORD | Already taken place Th, 7.5.2026
Explore icIEF-UV/MS workflows for biotherapeutic stability studies. Learn how to identify charge variants and degradation pathways in monoclonal antibodies with enhanced analytical confidence.
SCIEX: Assessing biotherapeutic stability through forced degradation using intact and subunit icIEF-UV/MS workflows
SCIEX: Assessing biotherapeutic stability through forced degradation using intact and subunit icIEF-UV/MS workflows

Biotherapeutic stability is essential for ensuring product quality, safety, and efficacy. In this webinar, discover how forced degradation studies combined with intact and subunit icIEF-UV/MS workflows provide deeper insights into charge variants and degradation pathways. Learn how integrating icIEF with UV and mass spectrometry enhances analytical confidence and supports robust biopharmaceutical characterization.

Key highlights

  • Understand how the icIEF-UV/MS method works to identify charge variants in 30 minutes
  • Discover how it has been applied to the analysis of an intact and the sub units of a stressed monoclonal antibody
  • Find out how the Biologics Explorer software aids data visualisation in both intact and subunit analysis

Speaker: Dr. Stephen Lock, Senior Market Development Manager, SCIEX

SCIEX
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