Targeted Proteomics: Tiny Samples, Big Accuracy: Large-Panel Targeted Proteomics with 6495D LC/TQ

RECORD | Already taken place Tu, 31.12.2024
Targeted LC-MS/MS enables highly sensitive quantitative proteomics of very small samples, including single cells.
Agilent Technologies: Choose Intelligence
Agilent Technologies: Choose Intelligence

Quantitative analysis of low amount samples such as single cell proteome requires highly sensitive instruments. Targeted quantification analysis using Evosep One, Newomics ion source and Agilent 6495D Triple Quadrupole LC/MS significantly increased method sensitivity. Enhanced acquisition software on 6495D LC/TQ enable 10K targeted transitions from over 1000 peptides in a method.

These improvements together greatly increase method selectivity, sensitivity and throughput for proteomic quantification in tiny samples.

Presenter: Linfeng Wu (LC/MS Application Scientist, Agilent)

Dr. Linfeng Wu received her Ph.D. in 2007 at University of Connecticut for Biomedical Sciences. After a post-doc training in Dr. Michael Snyder’s group at Stanford University, she worked as a research scientist in biotech industry. Dr. Wu joined Agilent in 2015 as an application scientist, focusing on LC/MS-based analysis for protein, proteomics and small molecule analysis.

Agilent Technologies
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