Live from the Lab: Spatial proteomics in action

RECORD | Already taken place Tu, 23.9.2025
Learn how cutting-edge spatial proteomics workflows integrate imaging, LMD, and LC-MS to achieve high-resolution, scalable analysis of 100 proteomes a day.
Bruker: Live from the Lab: Spatial proteomics in action
Bruker: Live from the Lab: Spatial proteomics in action

Spatial proteomics, which enables spatially and cell-type resolved protein profiling in tissue specimens, is the Nature Methods Method of the Year 2024. A particularly powerful methodology is the integration of advanced imaging with exploratory liquid chromatography-mass spectrometry (LC-MS) based proteomics. Current workflows allow the profiling of a few cells, such as cellular niches, and even single cell applications.

With such high-resolution methods, increasing sample throughput is essential and requires robust, reproducible, and scalable LC-MS workflows to cope with these demands.

In this webinar, learn from the experts in the field about:

  • Image processing and region co-registration for laser microdissection (LMD)
  • Sample capture and sample preparation
  • Proteome analysis on the Evosep Eno and timsUltra AIP, enabling a "100 spatial proteomes a day" workflow

Presenter: Melissa Klingeberg, Ph.D. Candidate, Coscia Lab, Max Delbrück Center for Molecular Medicine, Berlin, Germany


Presenter: Jose Nimo, Ph.D. Candidate, Coscia Lab, Max Delbrück Center for Molecular Medicine, Berlin, Germany


Presenter: Christoph Krisp, Ph.D., Application Development Specialist Single Cell Proteomics, MDC-Bruker Center of Excellence for Single Cell Omics, Berlin, Germany 

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