HPLC Reloaded: LC-MS Hyphenated Techniques for Biopharma

Here recent progress, challenges, and learnings from MS-based workflows at Symphogen will be present and illustrated through case-studies. A broad range of separation techniques are now routinely combined with mass spectrometry for in-depth biopharmaceutical characterization. Simultaneously, MS software tools have evolved to support storage, processing and reporting of the expanding MS data oceans.

Dr. Shane Bechler, Christof Mitterer, Maria Grübner, and Dr. Ken Cook from Thermo Fisher Scientific, and Dr. Dan Bach Kristensen from Symphogen, will discuss the recent progress, challenges, and learnings from MS-based workflows at Symphogen.

Additionally, they will present an overview of the technological highlights of a novel mono-disperse ion-exchange technology for both strong cation and anion exchanger. Applications for high-resolution charge profiling of biopharmaceutical modalities including charge variant analysis of monoclonal antibodies and recombinant proteins, and the determination of full and empty AAV viral vectors will also be explored.

Key learning objectives

• Learn about separation techniques for in-depth biopharmaceutical characterization
• Understand how MS software tools have evolved to support storage, processing and reporting of the expanding MS data
• Explore novel mono-disperse ion-exchange technology for both strong cation and anion exchanger

Who should attend?

• Lab managers and directors
• Principal scientists
• Laboratory analysts

Certificate of attendance

All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.

Presenter: Dr. Shane Bechler (Senior R&D Manager, Thermo Fisher Scientific)

Presenter: Christof Mitterer (Global product manager for BioLC columns and consumables, Thermo Fisher Scientific)

Presenter: Dr. Dan Bach Kristensen (Principal scientist, Symphogen, a part of Servier)

Presenter: Maria Grübner (Senior Product Applications Specialist, Thermo Fisher Scientific)

Presenter: Dr. Ken Cook (EU manager biopharma expert support group, Thermo Fisher Scientific)

Moderator: Carrie Haslam (Associate Editor, SelectScience)