As regulations evolve and PFAS analysis expands beyond traditional water testing, laboratories are adapting to new challenges across environmental, food and industrial sectors.Laboratories around the world are facing a new reality for <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/environmental/environmental-contaminant-analysis/emerging-contaminants/pfas-testing.html">PFAS analysis</a>. Expanding regulations, growing lists of compounds of concern, and increasing demand for analysis across environmental, food and industrial sectors mean many laboratories are being asked to do more than ever before.While these changes are global, Europe continues to play an important role in shaping the regulatory landscape. Since January 2026, EU Member States have been required to monitor PFAS levels in drinking water and ensure they remain within EU limits. Regulatory attention is also extending beyond drinking water to surface and groundwater, soil, packaging and industrial emissions, as outlined in the <a target="_blank" rel="noopener noreferrer" href="https://environment.ec.europa.eu/topics/chemicals/pfas-pollution_en">European Commission’s overview of PFAS pollution and EU action</a>.Although requirements differ by region, the direction is clear: laboratories are facing analytical questions involving more compounds and a wider range of matrices. For scientists looking to keep pace, our <a target="_blank" rel="noopener noreferrer" href="https://gateway.on24.com/wcc/eh/4080611/category/139628/pfas-testing?partnerref=E.25CMD.EL102.26305.01">PFAS resources</a> bring together webinars, application notes and expert insights across environmental, food and industrial testing.<h5>PFAS analysis is no longer defined by a single matrix or a single workflow.</h5><h3>PFAS analysis is expanding</h3>For many laboratories, PFAS analysis began with drinking water. Today, the scope has expanded considerably.Laboratories are increasingly working across drinking water, groundwater, surface water and wastewater, as well as food and food contact materials, cosmetics and personal care products, environmental samples, and industrial and consumer products.Each matrix presents different analytical challenges. Water analysis can require trace-level quantification, while complex food and consumer-product matrices may require different sample preparation or broader screening approaches. Techniques such as total organic fluorine (TOF) analysis can also provide a complementary perspective to targeted PFAS measurements.This diversity means there is no single analytical approach that answers every PFAS question.<h5>As PFAS analysis expands beyond drinking water, laboratories need approaches that can adapt to diverse sample types and evolving regulatory expectations.</h5><h3>Learning from the scientific community</h3>As laboratories respond to these changing analytical demands, many are exploring new approaches to longstanding challenges such as sample preparation.One example comes from Severn Trent Laboratories (Bridgend, UK), which implemented a PFAS workflow using Dispersive Liquid–Liquid Micro Extraction (DLLME). The approach provides an alternative to traditional solid phase extraction and can help reduce sample handling and solvent consumption.Laboratories interested in the approach can explore more information on <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/environmental/efox-analytical-solutions-platform/workflows.html">DLLME and PFAS workflows</a>.<h3>Watch the webinar</h3><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_2aeaa52248.jpg" alt="Thermo Fisher Scientific: PFAS Analysis Beyond Water: Meeting the Challenges of Environmental, Food and Industrial Testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_2aeaa52248.jpg 245w," sizes="100vw" width="800" height="347"><h4>Severn Trent / PFAS webinar</h4>EFOX approach for environmental workflows: PFAS &amp; emerging contaminantsHear more about this approach and explore wider developments in PFAS and emerging contaminant analysis.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6542">Watch on demand</a></h4></blockquote><h3>The changing PFAS landscape</h3>The changing analytical landscape extends well beyond sample preparation. Laboratories are simultaneously navigating evolving regulations, growing lists of compounds of interest, greater scrutiny of food and industrial materials, and increasing interest in broader screening approaches.Europe illustrates how these trends are converging. Alongside drinking-water requirements, EU action extends to industrial emissions and food-contact packaging. The Industrial Emissions Directive imposes stricter monitoring of PFAS emissions, with reporting requirements for PFOA, PFHxS and their salts from 2028. From August 2026, EU rules also ban food-contact packaging containing PFAS above specified concentration limits, as detailed in the <a target="_blank" rel="noopener noreferrer" href="https://environment.ec.europa.eu/topics/chemicals/pfas-pollution_en">European Commission’s overview of PFAS pollution and EU action</a>.Changes are also underway for Europe’s surface water and groundwater. Updated pollutant lists that entered into force in May 2026 include certain PFAS, including TFA, among substances to be monitored more closely and subject to stricter controls under the <a target="_blank" rel="noopener noreferrer" href="https://environment.ec.europa.eu/topics/water/water-framework-directive_en">EU Water Framework Directive.</a>The European picture also demonstrates why PFAS is no longer solely an environmental-water issue. PFAS have been widely used in products including food packaging, textiles, lubricants and batteries, while industrial activities that produce or use PFAS can contribute to environmental releases.Globally, regulatory requirements vary, but the analytical challenge is similar: laboratories need the flexibility to respond as both the compounds of interest and the matrices under investigation change.<h3>PFAS analysis across different sample types</h3>Different matrices raise different analytical questions—from selecting an appropriate sample preparation strategy to deciding between targeted quantification and broader screening approaches.<h4>Environmental and water PFAS analysis</h4><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_2_3ef68ae44e.jpg" alt="Thermo Fisher Scientific: PFAS Analysis Beyond Water: Meeting the Challenges of Environmental, Food and Industrial Testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_2_3ef68ae44e.jpg 245w," sizes="100vw" width="768" height="439">Explore analytical approaches for drinking water, groundwater, surface water and wastewater, including automated sample preparation and multi-matrix PFAS quantification.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/environmental/efox-analytical-solutions-platform/workflows.html">Automated DLLME for environmental PFAS analysis</a></li><li>Resource: <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/ab_004180_efs_orbitrap_exploris_efox_ab004180_em_en_932cc99eb4.pdf">Quantification of 61 PFAS across drinking water, groundwater, surface water and wastewater</a></li></ul><h4>Food and food contact materials PFAS analysis</h4><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_3_eb783dd0d3.jpg" alt="Thermo Fisher Scientific: PFAS Analysis Beyond Water: Meeting the Challenges of Environmental, Food and Industrial Testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_3_eb783dd0d3.jpg 245w," sizes="100vw" width="768" height="433">Explore PFAS analysis in food and food-contact materials, including total organic fluorine (TOF) screening and evolving approaches to investigating fluorinated compounds in packaging.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/5894">Enhancing PFAS analysis in food contact materials using combustion ion chromatography</a></li></ul><h4>Cosmetics / industrial PFAS analysis</h4><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_4_99a5bfea7e.jpg" alt="Thermo Fisher Scientific: PFAS Analysis Beyond Water: Meeting the Challenges of Environmental, Food and Industrial Testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_4_99a5bfea7e.jpg 245w," sizes="100vw" width="768" height="432">Explore approaches for investigating PFAS and total organic fluorine in complex matrices such as cosmetics and other consumer or industrial materials.<ul><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_004403_ic_cic_industrial_an004403_na_en_3c2419b88b.pdf">Total PFAS content in cosmetics using combustion ion chromatography</a></li></ul><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gateway.on24.com/wcc/eh/4080611/category/139628/pfas-testing?partnerref=E.25CMD.EL102.26305.01">Explore all PFAS resources</a></h4></blockquote><h3>Learn from experts</h3>As PFAS science and regulation continue to evolve, knowledge sharing across the scientific community is becoming increasingly valuable.<h4>Live from the Lab: Solutions for Environmental and Food Contaminant Analysis 2026</h4><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_5_3afde1ec49.jpg" alt="Thermo Fisher Scientific - PFAS Analysis Beyond Water - Meeting the Challenges of Environmental, Food and Industrial Testing 5.jpg" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_PFAS_Analysis_Beyond_Water_Meeting_the_Challenges_of_Environmental_Food_and_Industrial_Testing_5_3afde1ec49.jpg 245w," sizes="100vw" width="768" height="402">Join scientists from industry and academia to explore developments in environmental and food contaminant analysis. PFAS-focused discussions include regulatory trends, drinking water analysis, food-contact materials, workflow optimisation, source differentiation, and untargeted screening. Register to join us online or in person at one of our satellite events across Europe.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gateway.on24.com/wcc/eh/4080611/category/150288/lftl-event-environmental-and-food-contaminant-testing?partnerref=E.25CMD.EL102.26305.01">Register here: Live from the Lab: Solutions for Environmental and Food Contaminant Testing</a></h4></blockquote><h3>Looking ahead</h3>PFAS analysis is unlikely to become simpler. As regulations evolve and new areas of testing emerge, laboratories will continue to face broader analytical questions across environmental, food and industrial testing.Preparing for the future isn’t about predicting every regulatory change. It’s about developing the knowledge and flexibility to respond as new compounds, matrices and analytical questions emerge.How is your laboratory preparing for the next phase of PFAS analysis? Whether you’re responding to new regulations, expanding into different matrices or evaluating new analytical approaches, staying connected to developments across the scientific community can help you prepare for what’s next.<blockquote>Visit us on&nbsp;<a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/">LinkedIn:</a>&nbsp;#PFAS #PFASAnalysis #EnvironmentalTesting #FoodSafety</blockquote>

PFAS Analysis Beyond Water: Meeting the Challenges of Environmental, Food and Industrial Testing

Wiley, a global leader in authoritative content and research intelligence, today announced the launch of its spectral analysis application programming interface (API) portfolio, providing users with a new, faster way to access its trusted spectral data, analytical algorithms, and predictive models—within their own workflows.Wiley has one of the most comprehensive and trusted collections of scientific reference databases in the world, relied upon as a gold standard for identifying unknown chemical compounds by laboratories, instrument vendors, and software platforms across pharmaceuticals, forensics, environmental science, chemicals, food, materials, and other fields. The new portfolio extends the data and tools into modern, API-driven environments—allowing users to integrate high-quality spectral intelligence directly into their own systems and workflows.As sample volumes grow and lab workflows become more automated and software-driven, identifying and verifying compounds quickly and reliably becomes even more critical. The new API portfolio meets that need directly, giving labs and platforms a faster way to complete the process, whether catching a quality issue on a production line or identifying an unknown compound in the field. The result is less manual effort, faster analysis, and more confidence in the answer.The launch builds on Wiley's mission to transform knowledge into actionable intelligence for corporate and academic researchers around the world."Speed matters when you're trying to identify an unknown substance; a delayed analysis can mean an assembly line sitting idle or a forensic lab holding up a case,” said Armughan Rafat, Wiley senior vice president and chief AI and data services officer. “We've spent decades building the reference data this industry trusts. Now, by making that spectral data and analytical intelligence available through APIs, we're setting the standard for how labs and vendors turn unknowns into answers faster and at scale."<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_API_spectral_search_5bfcb1dd9b.png" alt="Wiley: spectral analysis API" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_API_spectral_search_5bfcb1dd9b.png 128w," sizes="100vw" width="802" height="977"><h5>The API portfolio launches with four core capabilities:</h5><ul><li>Spectral Database Search API – Query Wiley’s comprehensive reference collections for rapid compound identification.</li><li>Spectrum-Structure Validation API – Confirm proposed chemical structures against experimental spectral data.</li><li>Compound Classification API – Classify unknown substances, including drugs, based on compound class.</li><li>Spectra Prediction API – Generate predicted spectra to support research, method development, and validation.</li></ul>Unlike fragmented in-house databases or instrument-specific solutions, these APIs offer a continuously curated, vendor-neutral foundation that supports multi-technique workflows, regulatory compliance, and cross-platform interoperability. As a result, laboratories can increase throughput, minimize downtime, and protect the value of the instrumentation and data in which they've already invested.<h4>Spectral Databases &amp; APIs</h4>Spectral databases contain unique molecular “fingerprints” of substances captured through analytical techniques such as infrared (IR), mass spectrometry (MS), nuclear magnetic resonance (NMR), and Raman spectroscopy. By comparing experimental spectra against validated reference data, researchers can accurately identify unknown compounds across a wide range of applications.An API is a common way for computer systems, from lab instruments to software platforms, to request information from one another and get an answer back automatically.<blockquote>For more information about the Wiley spectral analysis API portfolio, please <a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/spectral-analysis-apis/">visit this website</a></blockquote><h4>About Wiley</h4>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning.&nbsp;

Wiley Launches Its First Spectral Analysis API Portfolio

ISC 2026 - Day 5

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

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Waters SARS-CoV-2 LC-MS Kit (RUO)

Advance virus research with Waters' RUO LC-MS kit for SARS-CoV-2. Detect and quantify NCAP peptides with high sensitivity and reproducibility using SISCAPA antibody enrichment and automation-ready workflows.

<h4>Detect and quantify SARS-CoV-2 NCAP peptides to advance virus research</h4>The global COVID-19 pandemic created an unprecedented need to quickly deploy emergency tests for SARS-CoV-2 infection. Now, scientists can harness the flexibility and reproducibility of LC-MS to advance critical SARS-CoV-2 research.Waters SARS-CoV-2 LC-MS Kit (RUO) is a Research Use Only kit to directly detect and quantify SARS-CoV-2 signature nucleocapsid peptides (NCAPs) without the need to amplify the target analytes – so you can ensure accuracy, reproducibility, and sensitivity for your most critical research.&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_SARS_Co_V_2_LC_MS_Kit_RUO_2_50b4ae9b00/Waters-SARS-CoV-2-LC-MS-Kit-(RUO)-2.jpg" alt="Waters: SARS-CoV-2 LC-MS Kit (RUO)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_SARS_Co_V_2_LC_MS_Kit_RUO_2_50b4ae9b00/thumbnail_Waters-SARS-CoV-2-LC-MS-Kit-(RUO)-2.jpg 234w," sizes="100vw" width="660" height="440"><h4>Overview</h4><ul><li>Achieve reproducible results between and within labs &nbsp;</li><li>Ensure high accuracy and analytical sensitivity to enable critical research &nbsp;</li><li>Empower research and development of pioneering SARS-CoV-2 testing with an alternative and complementary technology to common infectious pathogen research &nbsp;</li><li>Enable broader research with an LC-MS method with the potential to be multiplexed with other peptides and biomarkers&nbsp;</li></ul>* This kit is for research use only and has not been approved for use in clinical diagnostic procedures. This RUO kit has not been tested with clinical samples. The SARS-CoV-2 kit for SARS-CoV-2 nucleocapsid peptides is not available in all countries, please contact your Waters representative for more details.Recommended Use: For the detection and quantification of SARS-CoV-2 signature NCAP peptides.<h4>LC-MS enables cutting-edge SARS-CoV-2 research</h4>The Waters SARS-CoV-2 LC-MS Kit (RUO) is a Research Use Only kit intended for the quantitative measurement of three proteolytic peptides derived from the SARS-CoV-2 Nucleocapsid (NCAP) protein. The method has been optimized on an <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/199">ACQUITY UPLC I-Class PLUS</a> and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/195">Xevo TQ-XS System</a> and is also intended for use with the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/208">Andrew+ Pipetting Robot</a>. Optimization on other instrument platforms is possible. &nbsp;Further investigation is needed to collect objective evidence in promising research applications, however, based on the properties of the analytical test method, the SARS-CoV-2 LC-MS Kit might be leveraged for the following research studies: &nbsp;<ul><li>Peptide concentration to quantitate SARS CoV-2 signature peptides at different stages of infection&nbsp;</li><li>Research of infection and long-term effects through peptide quantitation&nbsp;</li></ul>Future pandemic preparedness studies and research of signature peptide-based biomarkers unique to other infections <img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_The_SARS_Co_V_2_LC_MS_Kit_RUO_allows_for_easy_sample_preparation_sample_enrichment_and_sample_detection_f0aca034ad.jpg" alt="Waters: The SARS-CoV-2 LC-MS Kit (RUO) allows for easy sample preparation, sample enrichment, and sample detection." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_The_SARS_Co_V_2_LC_MS_Kit_RUO_allows_for_easy_sample_preparation_sample_enrichment_and_sample_detection_f0aca034ad.jpg 234w," sizes="100vw" width="1024" height="682"><h4>Achieve confidence in results</h4>Ensure accurate and consistent results with highly analytically selective antibody magnetic bead enrichment. With the innovative SISCAPA® anti-peptide antibody enrichment sample preparation method from SISCAPA Assay Technologies, Inc. in the SARS-CoV-2 LC-MS Kit (RUO), you can improve the performance of mass spectrometry for measurement of pre-selected protein targets.With the SARS-CoV-2 LC-MS Kit (RUO) and SISCAPA, you can achieve the analytical sensitivity you need to detect low levels of SARS-CoV-2 peptides from complex digested samples with stable isotope standards and capture by anti-peptide antibodies. Increase laboratory efficiency with all the components your busy research laboratory needs to quickly deploy the supplied method - all in one package.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_The_SARS_Co_V_2_method_minimizes_sample_media_interference_providing_greater_flexibility_for_the_analysis_of_multiple_research_samples_fe3a56c686.jpg" alt="Waters: The SARS-CoV-2 method minimizes sample media interference, providing greater flexibility for the analysis of multiple research samples." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_The_SARS_Co_V_2_method_minimizes_sample_media_interference_providing_greater_flexibility_for_the_analysis_of_multiple_research_samples_fe3a56c686.jpg 234w," sizes="100vw" width="1024" height="682"><h4>Ensure reproducibility with trusted chemistries and consumables</h4>Ensuring reproducible quantitation from sample-to-sample, run-to-run, and lab-to-lab provides the confidence you need for critical research decisions. Ensuring reproducibility starts with minimizing variability risks, including the risk of unpredictable non-specific binding of peptides to surfaces. The SARS-CoV-2 LC-MS Kit uses QuanRecovery Plates with MaxPeak HPS and a MaxPeak Premier Peptide Column, minimizing non-specific binding of peptides to surfaces while enhancing recovery and signal.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_Analytical_sensitivity_of_the_ADE_AYN_and_NPA_peptides_in_VTM_at_2_3_5_10_and_20_amol_L_following_antibody_enrichment_145d5249ef.jpg" alt="Waters: Analytical sensitivity of the ADE, AYN, and NPA peptides in VTM at 2, 3, 5, 10, and 20 amolµL following antibody enrichment." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_Analytical_sensitivity_of_the_ADE_AYN_and_NPA_peptides_in_VTM_at_2_3_5_10_and_20_amol_L_following_antibody_enrichment_145d5249ef.jpg 234w," sizes="100vw" width="1024" height="682"><h4>Let Andrew+ pipette for you</h4>Save valuable time and focus on your research with reliable and reproducible sample preparation using the Andrew+ Pipetting Robot. The SARS-CoV-2 LC-MS Kit (RUO) comes in an automation-friendly format with liquid handling protocols for the Andrew+ Pipetting Robot available on OneLab.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Waters_SARS_Co_V_LC_MS_Kit_RUO_automation_protocol_available_for_Andrew_Pipetting_Robot_It_provides_a_flexible_automation_platform_easily_adaptable_to_multiple_workflows_8dca9a99e0.jpg" alt="Waters: SARS-CoV-LC-MS Kit (RUO) automation protocol available for Andrew + Pipetting Robot. It provides a flexible automation platform easily adaptable to multiple workflows." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Waters_SARS_Co_V_LC_MS_Kit_RUO_automation_protocol_available_for_Andrew_Pipetting_Robot_It_provides_a_flexible_automation_platform_easily_adaptable_to_multiple_workflows_8dca9a99e0.jpg 234w," sizes="100vw" width="1024" height="682">

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