Released N-linked Glycan Analysis Using the BioAccord System

[ APPLICATION NOTE ] Increasing Productivity and Confidence for N-linked Glycan Analysis of Biosimilars Using the BioAccord System Ximo Zhang, Corey Reed, Henry Shion, William Alley, Robert Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…

Application Note Improving Released N-glycan Analysis in Biotherapeutic Development Using the ACQUITY Premier Solution with MaxPeak High Performance Surfaces (HPS) Technology Ximo Zhang, Jacob Kellett, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Characterization and monitoring of glycosylation are…

IMPROVING CONFIDENCE AND PRODUCTIVITY FOR N-LINKED GLYCAN ANALYSIS IN BIOTHERAPEUTICS DEVELOPMENT USING AN INTEGRATED UPLC-FLR-HRMS SYSTEM Ximo Zhang; Corey Reed, Henry Shion, Robert Birdsall; Ying Qing Yu Scientific Operations, Waters Corporation, Milford, MA INTRODUCTION RESULTS AND DISCUSSION Due to the…

Application Note Improving UPLC-FLR-MS N-glycan Analysis of Disulfide-rich Fusion Proteins Through Optimization of Sample Preparation Ximo Zhang, Mauro Sassi, Erika Birolo, Nunzio Sepe, Paolo Felici, Angelo Palmese, Robert E. Birdsall, Ying Qing Yu Waters Corporation, Merck Abstract Fusion proteins represent…