NOVEL TISSUE WASHING PROCEDURE FOR THE REMOVAL OF CATION ADDUCTS PRIOR TO SELECTIVE CATION FORMATION FOR DESI AND MALDI IMAGING

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

[ APPLICATION NOTE ] DESI MS Imaging Using SONAR™: A Novel Method to Image Precursor Ions and Fragment Ions for Molecular Identification in a Single Experiment Emmanuelle Claude Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION DESI MS…

MALDI Mass Spectrometry Imaging Reveals Distinct Spatio-Molecular Phospholipid Distributions in Mouse Lungs While phospholipids play key roles in lung physiology and pathology, the complex composition and function of the lipidome in the lungs is poorly understood. We applied MALDI mass…

Application Note MALDI and DESI: Complementary Lipid Imaging on a Single Mass Spectrometry System Mark Towersa, Nuria Sliijkhuisb, Lisa Towersa, Emmanuelle Claudea, Joanne Ballantynea, Gijs Van Soestb a Waters Corporation, Wilmslow, United Kingdom b Department of Cardiology, Cardiovascular Institute, Thorax…