Rapid, Sensitive, and Routine Intact mAb Quantification using a Compact Tof HRMS Platform

[ APPLICATION NOTE ] High Sensitivity Intact Monoclonal Antibody (mAb) HRMS Quantification Yun Wang Alelyunas, Henry Shion, Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION mAb LC-MS method which enables Biotherapeutics have emerged as one of…

[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…

[ APPLICATION NOTE ] HRMS System Check for Intact Protein Quantification Armand Ngounou, Yun Alelyunas, and Mark Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ A system check (SC) ensures proper In recent years, there has been a…

[ TECHNOLOGY BRIEF ] Comparison of Tandem and High Resolution Mass Spectrometry for the Quantification of the Monoclonal Antibody, Trastuzumab in Plasma Mary Lame, Caitlin Dunning, Yun Alelyunas, and Mark Wrona Waters Corporation, Milford, MA, USA Demand for bioanalytical quantification…