A Comprehensive Approach for Monoclonal Antibody N-linked Glycan Analysis from Sample Preparation to Data Analysis

Agilent-NISTmAb Glycan Analysis Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate profile, charge variants…

Application Note Biotherapeutics and Biosimilars Profiling Glycosylation of Monoclonal Antibodies at Three Levels Using the Agilent 6545XT AdvanceBio LC/Q‑TOF Author Introduction David L. Wong Agilent Technologies, Inc. Santa Clara, CA, USA Monoclonal antibodies (mAbs) and their derivatives represent a very…

Agilent Biocolumns Glycan Analysis Application Compendium Contents Background 2 Getting Started 3 How to Guide - Glycan Mapping 4 Featured Application Notes 1 16 Streamlined Workflows for N-Glycan Analysis of Biotherapeutics Using Agilent AdvanceBio Gly-X InstantPC and 2-AB Express Sample…

Application Note Biopharma/Pharma Automated Workflow for Monoclonal Antibody N-Linked Glycan Analysis Authors Shuai Wu, Zach Van Den Heuvel, Steve Murphy, and Aled Jones Agilent Technologies, Inc. Abstract This application note describes an automated workflow for the release, labeling, and cleanup…