AdvanceBio HIC: a Hydrophobic HPLC Column for Monoclonal Antibody (mAb) Variant Analysis

Agilent-NISTmAb Intact Analysis Using Hydrophobic Interaction Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate…

Sandeep kondaveetil1, Andy Coffey2, Priya Jayaraman1, Linda Llyod2, Suma Ramagiri1 Hydrophobic Interaction Chromatography- Native Mode Separation of Bio-Therapeutic Workflows 1. Agilent Technologies, Inc., Wilmington, DE USA 2. Agilent Technologies, Inc., Church Stretton, UK Experimental LC Conditions – mAb oxidized variant…

Agilent BioHPLC Columns Characterization of NIST Monoclonal Antibody Critical Quality Attributes Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…

Why Use HILIC and HIC Chromatography? Theory and method development strategies Mohit Patel, PhD LC Applications Engineer October 8, 2024 1 10/08/2024 DE-001530 AGILENT CONFIDENTIAL Agenda 1 What is HILIC and when should you consider it? 2 How to approach…