Evaluation of a rapid LC-MS/MS method to measure simultaneously IDUA and IDS enzymes activities in dried blood spots

MP 083 A rapid LC-MS/MS method to measure simultaneously IDUA, IDS, NAGLU, GALNS and ASRB enzymes activities in dried blood spots Misa Tanaka1，Jun Watanabe2 ， Tetsuo Iida2， Hironori Kobayashi3 1 MS Specialite, Kanagawa, Japan, 2 Shimadzu Corporation, Kyoto, Japan, 3…

PO-CON1718E Comparison of FIA and on-column LC-MS/MS method to measure simultaneously ABG, ASM, GAA, GALC, GLA and IDUA activities ASMS 2017 ThP 091 Misa Tanaka, Jun Watanabe, Toshikazu Minohata, Junichi Masuda, Eishi Imoto Shimadzu Corporation. 1, Nishinokyo-Kuwabaracho Nakagyo-ku, Kyoto 604-8511,…

WP 097 Development of Glycosaminoglycans Analysis Method for Dried blood spot as a Second-tier Test in Mucopolysaccharidoses Screening Hironori Kobayashi1,2; Misa Tanaka1; Ryota Okazaki2; Tsubasa Oguni2; Miki Matsui1; Yoshitomo Notsu2; Shozo Yano2; Akihiro Kunisawa3; Michelle Zipse4; Takanari Hattori3; Jun Watanabe3;…

LAAN-A-LM-E110 Application News C139 No. Liquid Chromatography Mass Spectrometry Measurement of Enzymatic Activities in Dried Blood Spots with On-Line Solid Phase Extraction-LC/MS/MS System Lysosomes are a type of intracellular organelle that uses a variety of hydrolytic enzymes to digest waste…