Workflow solutions for released N-glycan profiling

[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…

Application Note Automated High-Throughput N-Glycan Labelling and LC-MS Analysis for Protein A Purified Monoclonal Antibodies Caitlin M. Hanna, Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract N-Glycans are routinely monitored during the development of biotherapeutics because they can affect…

[ APPLICATION NOTE ] Increasing Productivity and Confidence for N-linked Glycan Analysis of Biosimilars Using the BioAccord System Ximo Zhang, Corey Reed, Henry Shion, William Alley, Robert Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…

Application Note Similis Bio - Streamlined mAb Subunit LCMS Workflow for Multiple Attribute Monitoring of Biosimilar mAb Candidates During Bioprocessing and Development Samantha Ippoliti, Jared Young, Katy McNally, Caitlin Hanna, Ying Qing Yu, Bradley Prater, Mark D. Wrona, Emma Harry…