Qualitative Characterization and Quantitative Assessment of Monoclonal Antibodies Using Protein Metrics and nSMOLcoupled with the Shimadzu LCMS-9030 QTOF

An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements Application Note Biotherapeutics and Biosimilars Authors Introduction Shuai Wu and Maryann Shen Monoclonal antibody (mAb) based entities represent a rapidly growing class of biologics that require extensive…

Agilent-NISTmAb Intact & Subunit Analysis Using Reversed Phase Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…

No. SSI-LCMS-103 SSI-LCMS-103 Liquid Chromatography Mass Spectrometry Monoclonal Antibody Workflows on the Shimadzu Q-TOF LCMSTM-9030 Using the Protein Metrics Software Suite No. LCMS-103 Stephen Kurzyniec, Vikki Johnson Shimadzu Scientific Instruments, Inc. ■ Abstract Accurate characterization of monoclonal antibodies is essential…

Application Note Pharma & Biopharma Critical Quality Attribute Monitoring of mAbs at the Intact and Subunit Levels Using a Cost-Effective, Simple and Robust LC/MS Solution Authors Linfeng Wu, Lisa Zang, and Guannan Li Agilent Technologies, Inc. Abstract Recombinant monoclonal antibodies…