On-line Comprehensive RP-LC×RP-LC/IT-TOF for the Analysis of Proteome Isoforms

Application Handbook Liquid Chromatography Introduction HPLC, UHPLC as well as SFC systems are able to quantitatively analyze substances in mixtures containing multiple ingredients by separating and detecting target substances. They are used to separate, quantify, qualify or purify single components…

Analysis of E.coli Tryptic Digest and Intact Protein Using the Agilent 1290 Infinity 2D-LC Solution with Diode Array Detection and Q-TOF LC/MS Application Note Proteomics & Protein Sciences Authors Abstract Gerd Vanhoenacker1, Koen Sandra1,2 , 1,2 1 Isabel Vandenheede ,…

Application Note Biologics Examining the Structural Influence of Site-Specific Phosphorylation by Ion Mobility Mass Spectrometry Authors Rebecca S. Glaskin, Caroline S. Chu, and Dawn M. Stickle Agilent Technologies, Inc. Abstract This application note describes an automated workflow for the analysis…

Advancing Host Cell Protein Analyses Through the Combined Use of Microscale 2D RP/RP with CSH C18 and Ion Mobility Enabled MS Detection Matthew A. Lauber, Catalin E. Doneanu, Stephan M. Koza, Weibin Chen, and Kenneth J. Fountain Waters Corporation, Milford,…