Fast Analysis of Therapeutic Monoclonal Antibodies, Fragments, and Oxidation Variants Using a Super-Macro Porous Reversed-Phase Column Coupled with an Orbitrap Mass Spectrometer

There is a growing trend to obtain intact mass information as well as the glycan profile in the QC of mAbs using high resolution mass spectrometers. The most commonly employed LC/MS method is to desalt mAbs via reverse phase liquid…

See your protein therapeutics in high resolution Bio LC Columns Contents 2 Introduction to monoclonal antibody (mAb) characterization 3 Affinity titer determination 4 Aggregate separation 5 Charge variant analysis 6 Oxidation variant analysis 11 Antibody drug conjugates (ADCs) analysis 12…

(U)HPLC columns SurePac Protein RP MDi columns Product manual Contents 2 Introduction Introduction to the column Operating limits and specification 3 3 3 Getting started 4 Column care 6 Applications Optimization for protein separations Loading capacity Ruggedness Lot-to-lot reproducibility Competitor…

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