Targeted Quantification of Peptides from Complex Biological Sample Using Q Exactive, a Routine Bench Top Quadrupole-Orbitrap Mass Spectrometer

Targeted Quantitative Proteomics Targeted protein quantification with high-resolution, accurate-mass MS Highly selective • Very sensitive • Complex samples HR/AM A more complete quantitative proteomics picture Many of the limitations associated with traditional SRM assays for the verification stage of the…

Application Note: 509 Absolute Quantification of Eicosanoid Pathway Proteins Using a Linear Ion Trap Mass Spectrometer Roger G. Biringer1, Julie Horner1, Alfred N. Fonteh2 , Stephen Kauffman 2 , Andreas F. R. Hühmer1, Michael G. Harrington 2 1 Thermo Fisher…

Targeted Protein Quantitation Using High-Resolution, Accurate-Mass Selected Ion Monitoring with Scheduled MS/MS on a New Hybrid Ion Trap-FTMS Mass Spectrometer P1085 Reiko Kiyonami1, Martin Zeller2, Vlad Zabrouskov1 1Thermo Fisher Scientific, San Jose, CA; 2 Thermo Fisher Scientific, Bremen, Germany Overview…

Large Scale Targeted Protein Quantification Using HR/AM Selected Ion Monitoring with MS/MS Confirmation on the Orbitrap Fusion Tribrid MS R. Kiyonami,1 M. Senko,1 V. Zabrouskov,1 J. Egertson, 2 S. Ting, 2 M. MacCoss, 2 A. FR Hühmer1 Thermo Fisher Scientific,…