Configuring the NanoLC™ 425 System for Both Nanoflow and Microflow LC-MS Workflows

TECHNICAL NOTE 72899 Tandem nanoLC-MS: maximum MS utilization for deep-dive proteomic analysis Table of Contents Authors Christopher Pynn , Alexander Boychenko1, Wim Decrop1, Mike Baynham2, Peter Jehle1, Martin Ruehl1 1 Thermo Fisher Scientific, Germering, Germany 1 Thermo Fisher Scientific, Runcorn,…

Multidimensional LC for separation of protein digests – A technical description of the Agilent 1100 Series nanoflow LC/MS system Technical Overview Abstract Today, multidimensional LC/MS is a well-established tool for proteome identification. For samples of lower complexity one-dimensional enrichment LC/MS…

Microflow SWATH® Acquisition for Industrialized Quantitative Proteomics NanoLC™ 400 System with TripleTOF® 6600 System Christie L Hunter1, Nick Morrice2 1 SCIEX, USA, 2SCIEX, UK Data independent acquisition (DIA) strategies have been used to increase the comprehensiveness of data collection while…

Microflow SWATH® Acquisition for Industrialized Quantitative Proteomics NanoLC™ 400 System with TripleTOF® 6600 System Christie L Hunter1, Nick Morrice2 1 SCIEX, USA, 2SCIEX, UK Data independent acquisition (DIA) strategies have been used to increase the comprehensiveness of data collection while…