Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat Plasma

Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Samples from Lean, Fat, and Obese Zucker Rat Plasma John Heim, Jeff Patrick, and Joe Binkley • Saint Joseph, MI USA OBJECTIVES Demonstrate the enhanced detection and increased peak…

Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Plasma Samples from Lean, Fat, and Obese Rats LECO Corporation; Saint Joseph, Michigan USA Keywords: GCxGC, Metabolomics, Biomarkers 1. Introduction 2. Experimental Conditions This GCxGC-TOFMS research presents the comparison…

Evaluation of Metabolite Variation by a Pooled Sample Approach between Normal Control and Traumatic Brain Injury Mice Using GCxGC-TOFMS with Data Analysis Using a Software Driven Reference Feature John Heim, Joe Binkley, and Liz Humston-Fulmer | LECO Corporation, Saint Joseph,…

GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury Study John Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USA INTRODUCTION METHODS Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry has…