GCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic and Non-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate Analysis

® Small Molecule Metabolite Identifications in Diabetic Versus Non-Diabetic Urine Sample Groups Using Comprehensive Two-Dimensional Gas Chromatography Combined with Time-of-Flight Mass Spectrometry (GCxGC-TOFMS) John Heim, LECO Corporation; Saint Joseph, Michigan USA Key Words: Fisher Ratio, Sample Groups, Diabetes, Metabolite Profile…

® Delivering the Right Results Utilization of Comprehensive Two-Dimensional Gas Chromatography Combined with Time of Flight Mass Spectrometry (GCxGC-TOFMS) for Small Metabolite Identifications in Complex Biological Samples John Heim and Mark Libardoni • LECO Corporation, St. Joseph, MI INTRODUCTION EXPERIMENTAL…

® Utilization of Statistical Compare Software and Fisher Ratios Prior to Multivariate Analysis for Complex GCxGCTOFMS Data in Order to Define Statistical Variation Between the Small Molecule Metabolite Profiles of Different Fish Species John Heim • LECO Corporation; Saint Joseph,…

Evaluation of Metabolite Variation by a Pooled Sample Approach between Normal Control and Traumatic Brain Injury Mice Using GCxGC-TOFMS with Data Analysis Using a Software Driven Reference Feature John Heim, Joe Binkley, and Liz Humston-Fulmer | LECO Corporation, Saint Joseph,…