HRAM LC-MS method for the determination of nitrosamine impurities in drugs

APPLICATION NOTE 000362 Reliable quantitation of 11 nitrosamine impurities in metformin drug products using Orbitrap Exploris 120 mass spectrometry Authors: Hao Yang,1 Jon Bardsley,2 Min Du,3 Thermo Fisher Scientific, San Jose, CA, US Thermo Fisher Scientific, Hemel Hempstead, UK 3…

Nitrosamine impurities analysis using Thermo Scientific™ Orbitrap Exploris™ 120 MS Hao Yang, Ph.D. Sr. Application Scientist Biopharma and Pharma Vertical Marketing The world leader in serving science 1 Application: Nitrosamine impurities analysis Liquid chromatography high resolution mass spectrometry (LC-HRMS) method…

APPLICATION NOTE 74059 Highly sensitive and robust LC-MS/MS solution for quantitation of nitrosamine impurities in metformin drug products Authors: Hao Yang1, Edmund Moy1, Michael Volny1, Claudia Martins1, Min Du2, Wael Elmasri3, Tanya Tadey4 Thermo Fisher Scientific, San Jose, CA; Thermo…

APPLICATION NOTE 10753 A validated method for the rapid determination of fifteen nitrosamines in metformin drug substance Authors: Dujuan Lu¹, Danny Hower1, Aaron Lamb2, Andrea Romano3, Dominic Roberts2 and Cristian Cojocariu2; 1 SGS, Fairfield NJ, USA, 2 Thermo Fisher Scientific,…