Quantification of Nitrosamine Impurities in Metformin Using Agilent GC/MS/MS Instrumentation

Nitrosamine Impurities Application Guide Confidently Detect and Quantify Mutagenic Impurities in APIs and Drug Products Sartan-Based Losartan Valsartan Candesartan Telmisartan Metformin Ranitidine Nitrosamines are formed by chemical reactions that occur during API manufacturing whether from starting materials, intermediates, reactants, reuse…

Application Note Pharma & Biopharma Quantification of Nine Nitrosamine Impurities in Sartan Drugs Using an Agilent GC-TQ Authors Soma Dasgupta, Vivek Dhyani, and Melissa Churley Agilent Technologies, Inc. Abstract In this application note, a method for the analysis of nine…

Application Note Pharmaceuticals Simultaneous Estimation of Eleven Nitrosamine Impurities in Metformin Drug Product Using an Agilent 6495D LC/TQ Authors Abstract Preeti Bharatiya, Prasanth Joseph, Vivek Dhyani, and Saikat Banerjee Agilent Technologies, Inc. This application note presents a comprehensive analytical method…

Application Note Pharmaceutical Small Molecules Simultaneous Determination of Eight Nitrosamine Impurities in Metformin Extended-Release Tablets Using the Agilent 6470 Triple Quadrupole LC/MS Detection of regulated genotoxic impurities from the drug manufacturing process Authors Chander Mani, Kartheek Srinivas Chidella, Saikat Banerjee,…