Guide to Size-Exclusion Chromatography (SEC) of mAb Aggregates, Monomers, and Fragments

2023–2024 Chromatography Columns and Supplies Catalog Table of Contents Sample Preparation 51 Sample Vials and Accessories 83 How to Choose a Column 93 MaxPeak Premier Columns 105 Sub-2-µm UPLC Columns 129 2.× µm UHPLC Columns 179 ≥3 µm Analytical HPLC…

Biomolecule Purification, Characterization, and Analysis Innovative Technologies from the Leader in Separation Science and Analytical Biochemistry Advances in the areas of genomics, proteomics, metabolomics, and molecular and system biology continue to revolutionize the diagnosis and treatment of diseases and increase…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…

[ CARE AND USE MANUAL ] BioResolve SEC mAb Guard and Columns CONTENTS I. INTRODUCTION II. SEC ANALYSIS OF MONOCLONAL IgG ANTIBODY AGGREGATES, MONOMERS, AND FRAGMENTS a. Considerations b. Determining Extra-Column LC System Dispersion c. Selecting the Appropriate …