Detection of extractables and leachables in drug products using the SCIEX Triple Quad™ 3500 LC-MS/MS System

Application Note Pharmaceuticals Determination of Extractable and Leachable Elements Using ICP-MS Analysis of elemental impurities from plastic ophthalmic drug containers using an Agilent 7900 ICP-MS Authors Paige Solomon University of California, San Francisco, CA, USA Jenny Nelson Agilent Technologies, Inc.…

Application of an Accurate Mass Database and Library for the Screening and Verification of Extractables and Leachables in Pharmaceutical Drug Products Application Note Pharmaceuticals Authors Abstract Syed Salman Lateef1, This Application Note describes the creation of an accurate mass library…

Extractables and Leachables Detected in Ophthalmic Drug Products Detection and Identification Using High-Resolution LC/MS/MS Application Note Pharmaceuticals Author Abstract Syed Salman Lateef Compounds leaching from container closure systems can cause contamination Agilent Technologies, Ltd. to drug substances or products. As…

Application News No. AD-0215 Pharmaceuticals / TD-30 & GCMS-QP2020 NX Thermal Desorption – GC/MS Method for Screening Analysis of Extractables in Drug Packaging Materials Cynthia Lahey1, Elgin Ting1, Dheeraj Handique2, Yuvanesh Kumar3, Yukihiko Kudo4 1Shimadzu (Asia Pacific) Pte Ltd, Singapore,…