Highly sensitive LC-MS/MS method for the quantification of barnidipine in human plasma, using the SCIEX QTRAP® 6500+ System

Highly Sensitive LC-MS/MS Method for Quantification of Barnidipine in Human Plasma Using the SCIEX QTRAP® 6500+ System with ExionLC™ AD System M Chandrasekar, Dilip Reddy, Manoj Pillai1 SCIEX, India Barnidipine is a long-acting novel calcium antagonist that belongs to the…

Improve Sensitivity for Quantification of Antisense Oligonucleotides in Plasma Using Microflow LC-MRM Methodology Ji Jiang, Sean McCarthy, Esme Candish, Lei Xiong SCIEX, 500 Old Connecticut Path, Framingham, MA 01520 INTRODUCTION Oligonucleotide therapeutics are rapidly growing as a class of therapeutic…

Sensitive Quantification of Therapeutic Oligonucleotides Extracted from Plasma Featuring the SCIEX QTRAP® 6500+ LC-MS/MS System Esme Candish1, Ji Jiang1, Andrew Hart2, Susovan Mohapatra2 1 SCIEX, Framingham MA, USA, 2 Wave Life Sciences, Lexington, MA, USA Oligonucleotide therapeutics and gene therapies…

For Research Use Only. Not For Use In Diagnostic Procedures Drug Discovery and Development Sensitive and Accurate Quantitation of the Antibody-Drug Conjugate Ado-Trastuzumab Emtansine in Rat Plasma High-Sensitivity Bioanalysis of ADC using BioBA with M3 MicroLC and QTRAP® 6500+ LC-MS/MS…