IMPROVED PERFORMANCE OF MODERN MS-COMPATIBLE REVERSED-PHASE/ANION-EXCHANGE MIXED-MODE HPLC COLUMNS

EVALUATION OF NEW MS-COMPATIBLE MIXED-MODE RP/AX HPLC COLUMNS Thomas H. Walter1, Bonnie A. Alden1, Melvin Blaze1, Cheryl Boissel1, Donna Osterman1, Amit V. Patel1, Paul Rainville2, Kerri M. Smith2, Jinchuan Yang2 1 Chemistry Operations, Waters Corporation, Milford, MA, USA, 2Scientific Operations,…

[ APPLICATION NOTE ] A New Mixed-Mode Reversed-Phase/Anion-Exchange Stationary Phase Based on Hybrid Particles Thomas H. Walter, Bonnie A. Alden, Cheryl Boissel, Jessica Field, Nicole Lawrence, Donna Osterman, and Amit Patel Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■…

MaxPeak Premier Columns Small Molecule Application Notebook CONTENTS Introduction Non-Specific Adsorption: Unwanted Interactions................................................................................... 3 How Do Scientists Solve This Problem Today?......................................................................................... 4 Precision Chemistry for Particles and Surfaces........................................................................................ 5 Fundamentals Waters™ Premier Standards to Investigate the Inertness of Chromatographic Systems....................................................................................................................................7…

[ TECHNOLOGY BRIEF ] Utilization of MaxPeak High Performance Surfaces and the Atlantis PREMIER BEH C18 AX Column to Increase Sensitivity of LC-MS Analysis Kerri M. Smith and Paul Rainville Waters Corporation, Milford, MA, USA MaxPeak High Performance Surfaces (HPS)…