Thermo Scientific Extractables & Leachables Workflow

Pharma and biopharma Solutions for pharmaceutical, medical device extractables and leachables analysis Enhance your capabilities Unknown impurity identification and quantification workflows for: • Pharmaceutical, packaging and contact-closure materials • Medical devices Contents Pharmaceutical contact-closure materials Semi-volatiles Medical devices Non-volatiles Per-…

APPLICATION NOTE 000206 Non-targeted screening of extractables from vial septa using high-resolution Orbitrap GC-MS Authors: Jane Cooper, Cristian Cojocariu, and Dominic Roberts Thermo Fisher Scientific, Hemel Hempstead, UK Keywords: High-resolution accurate mass, HRAM, gas chromatography, accurate mass, GC, Orbitrap Exploris…

and accurate differential analysis to be performed to isolate unique features in extracts. Routine mass resolution of 60,000 FWHM and consistent sub-ppm mass accuracy ensures selective and confident compound detection and identification. POSTER NOTE Introduction The investigation of potentially toxic…

Dominic Roberts,1 Andrew Feilden,2 Richard Barlow,2 Kyle D’Silva,1 and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK 2 Smithers Rapra, Shawbury, UK Key Words Extractables and Leachables, Q Exactive GC, Orbitrap mass spectrometry, differential analysis, unknown identification, container closure system,…