GLP-1 Analog: Accelerating Method Development and Manufacturing with LC-UV/MS

[ APPLICATION NOTE ] Improving Routine Analysis of Insulin Analogues Using the ACQUITY QDa Detector Ximo Zhang, Robert Birdsall, and Yinq Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ A cost-effective solution for improving Since its FDA…

LC-UV/MS Workflows Enabling Orthogonal Impurity Profiling of GLP-1 Analogs Duanduan Han, Robert Birdsall ,Nikhil Bhiwankar Affiliation: Waters Corporation, Milford, MA Introduction Results & Discussion Orthogonal screening for impurity detection • GLP-1 analog: exenatide (exe) Formula: C184H282N50O60S MW = 4,186.6 Da…

Analysis of Disperse Dyes Using the ACQUITY Arc System with PDA and Mass Detection, and Empower Software Marian Twohig,1 Michael O’Leary,1 and Jane Cooper2 Waters Corporation, Milford, MA, USA 2 Waters Corporation, Wilmslow, UK 1 A P P L I…

Forced Degradation Analysis of Omeprazole Using CORTECS 2.7 µm Columns Kenneth D. Berthelette, Thomas Swann, and Kenneth J. Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E N E F I…