Rapid High-Throughput Amino Acid Analysis of GLP-1 Analogs

LC-UV/MS Workflows Enabling Orthogonal Impurity Profiling of GLP-1 Analogs Duanduan Han, Robert Birdsall ,Nikhil Bhiwankar Affiliation: Waters Corporation, Milford, MA Introduction Results & Discussion Orthogonal screening for impurity detection • GLP-1 analog: exenatide (exe) Formula: C184H282N50O60S MW = 4,186.6 Da…

Application Note Application of LC-UV/MS Workflows to Increase Efficiency in Impurity Profiling of GLP-1 Analogs Duanduan Han, Samantha Ippoliti, Robert E. Birdsall, Karen Nyholm Waters Corporation, United States Published on May 16, 2025 Contact Sales Abstract Glucagon-like-peptide-1 (GLP-1) receptor agonists…

Application Note Accelerating Method Development and Manufacturing of GLP-1 Analogs with LCUV/MS Duanduan Han, Samantha Ippoliti, Robert E. Birdsall, Karen Nyholm Waters Corporation United States Published on May 14, 2025 Contact Sales Abstract Glucagon-like-peptide-1 (GLP-1) receptor agonists have recently gained…

[ APPLICATION NOTEBOOK ] Amino Acid Analysis Application Notebook [ CONTENTS ] [ INTRODUCTION ] Waters UPLC Amino Acid Analysis Solution................................................................................9 UPLC Amino Acid Analysis Solution............................................................................................... 11 Enhancement of the UPLC Amino Acid Analysis Solution with Flexible Detector Options......................................................................................................... 15…