Optimized XL-MS workflows for heterobifunctional crosslinkers SDA and DizSEC

LC separation optimization for XL-MS Analysis Yi He1, Erum Raja2, Leigh Foster2, Max Ruwolt3, Anthony Ciancone4, Fan Liu3, Francis O’Reilly4, Ryan Bomgarden2, Rosa Viner1 1Thermo Fisher Scientific, San Jose, CA, USA; 2Thermo Fisher Scientific, Rockford, Illinois, USA; 3Department of Structural…

Crosslinking mass spectrometry Optimized quantitative XL-MS Analysis on an Orbitrap Tribrid Apex mass spectrometer Yi He, Nicolas Hartal, Graeme McAlister, Rafael Maleni, Weijing Liu Thermo Fisher Scientific, San Jose, CA Abstract Results Purpose: To optimize the quantitative XL-MS workflows with…

Technical note | TN003979 Omics Proteome wide interactomics analysis using MS-cleavable crosslinkers and the Orbitrap Astral Zoom mass spectrometer Authors Goal Yi He , Tabiwang N. Arrey , Eugen Develop an end-to-end crosslinking mass spectrometry (XL-MS) workflow for MS-cleavable Damoc2,…

P-II-0592 Membrane protein analysis Novel XL-MS analysis workflows for membrane protein characterization Yi He1, Weijing Liu1, Donggyun Kim2, Vadim Cherezov2, Gregory J Dodge3, Barbara Imperiali3, Susan Leonhardt4, Mark Yeager 4, Rosa Viner1 1Thermo Fisher Scientific, San Jose, CA; 2Bridge Institute,…