Improved Bioanalytical Performance Using a Simplified 2-Step Oasis™ PRiME HLB Protocol with an Ultra-Short UPLC Column for UPLC-MS/MS

Application Note A Simplified Approach to Optimizing the Oasis PRiME HLB 2 Step Protocol to Maximize Recoveries Nikunj Tanna, Chelsea Plummer Waters Corporation Abstract Oasis™ PRiME HLB SPE removes >95% phospholipids from biological matrices, while maintaining the reversedphase selectivity of…

[ APPLICATION NOTE ] Quantitative Analysis of THC and its Metabolites in Whole Blood Using LC-MS/MS for Toxicology and Forensic Laboratories Xin Zhang, Jonathan P. Danaceau, and Erin E. Chambers Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Faster,…

AUTOMATION OF BIOANALYTICAL SAMPLE EXTRACTION TECHNIQUES USING ANDREW+™ PIPETTING ROBOT WITH THE EXTRACTION+ CONNECTED DEVICE Jonathan P. Danaceau and Mary E. Trudeau Waters Corporation, 34 Maple Street, Milford, MA , USA INTRODUCTION AUTOMATED SAMPLE PREPARATION AND EXTRACTION Bioanalytical sample preparation…

Analysis of Plasma 17-Hydroxyprogesterone, Androstenedione, and Cortisol Using a Novel Solid-Phase Extraction (SPE) Sorbent, Oasis PRiME HLB, for UPLC-MS/MS Analysis in Clinical Research Jonathan P. Danaceau and Erin E. Chambers Waters Corporation, Milford, MA, USA A P P L I…