Quantitative Analysis of Four Long-Chain Lysophosphatidylcholines (LPCs) in Dried Blood Spot using Liquid Chromatography Tandem Mass Spectrometry for Clinical Research

PARALLEL COLUMN REGENERATION: INCREASING THROUGHPUT IN CLINICAL RESEARCH WITHOUT SUCCUMBING TO MATRIX CONTAMINATION Heather Brown, Robert Wardle, Anahi Santoyo-Castelazo, Matthew Gill, Daniel Kenny and Lisa Calton Waters Corporation, Wilmslow, Cheshire, UK. INTRODUCTION Typical gradient separation methods include a regeneration segment…

QUANTITATIVE MEASUREMENT OF DRIED BLOOD SPOT GUANIDINOACETATE AND CREATINE FOR CLINICAL RESEARCH A.Santoyo Castelazo1, R. McBrinn1, J. Nisbet-Fahy1, E. Brennan2, R. Mahon2, E. McGleenan2, N. Stafford2 and A. Wynn3 1 Waters, Wilmslow, Cheshire, UK. 2Waters Chromatography Ireland Limited, IDA Business…

Analytical performance evaluation of the Waters AA/AC RUO kit for the measurement of biological metabolites in dried blood spots, by FIA-MS/MS Authors: Padhraic Rossiter1, Niamh Stafford1, Rachel McBrinn2, Heather Brown2 Affiliation: 1Waters Technology, Wexford, Ireland 2Clinical Business Unit, R&D, Waters…

[ TECHNOLOGY BRIEF ] Rapid UPLC-MS/MS Dried Blood Spot Analysis of Steroid Hormones for Clinical Research Dominic Foley, Heather Brown, and Lisa Calton Waters Corporation, Wilmslow, UK Rapid separation and analysis of steroid hormones in dried blood spots was achieved…