Enhanced tissue compartmentalization by applying segmentation algorithms on reduced spatial omics data

25 YEARS MALDI High-performance MALDI imaging analysis of on-tissue digested proteins in mammalian FFPE tissues using the Bruker rapifleX MALDI-TOF/TOF In this application note, we describe a workflow for MALDI Mass Spectrometry Imaging (MSI) of proteins from a variety of…

MALDI Guided SpatialOMx uncovers proteomic profiles in tumor subpopulations of breast cancer MALDI Guided SpatialOMx provides an excellent possibility to discover deep proteomics insights into heterogeneous tumor subpopulations by retaining the regiospecific information of an imaging technique. Abstract The timsTOF…

LI F E S CI E N CE S M AS S S P E CTR O M E TR Y Exploring the Aβ Plaque microenvironment in Alzheimer's disease model mice by multimodal Lipid-Protein-Histology Imaging on a benchtop mass spectrometer…

LI F E S CI E N CE S M AS S S P E CTR O M E TR Y Rapid spatial molecular insights into human brain tumors by axial MALDI TOF mass spectrometry imaging Jasmine Reese1, Janina Oetjen2,…