Monitoring Monoclonal Antibody Heterogeneity by Cation-Exchange Chromatography

User Manual ProPac WCX-10 and SCX-10 031410 Revision 08 • October 2015 For Research Use Only. Not for use in diagnostic procedures. Product Manual for ProPac WCX-10 and ProPac SCX-10 Page 2 of 30 PRODUCT MANUAL FOR PROPAC® WCX-10 AND…

APPLICATION NOTE 21684 K KK Using the NISTmAb reference standard to demonstrate a simple approach to charge variant analysis Authors Silvia Millán, Amy Farrell, and Jonathan Bones Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing Research and…

Analysis of Intact and C-terminal Digested IgG1 on an Agilent Bio MAb 5 µm Column Application Note BioPharma Authors Abstract Xiaomi Xu and Phu T Duong Nearly all proteins undergo modifications after translation from mRNA. The Agilent Technologies, Inc. modifications…

Application Note 177 Separation of an Intact Monoclonal Antibody and Fractionation of Monoclonal Antibody Papain Digest Fragments Using Immobilized Metal Affinity Chromatography (IMAC) INTRODUCTION Monoclonal antibodies (MAbs) have been indispensable for the development of a wide range of products in…