Protein-Protein Interactions

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…

Protein Solutions™ Heat-Shock Proteins/Molecular Chaperones Molar Mass vs. Volume HS25 HS40 HS70 1.0x106 Molar Mass (g/mol) 25° 40° 75° 1.0x105 8.4 8.6 8.8 9.0 9.2 9.4 Volume (mL) Figure 1. MM of the Mj sHSP complex measured by MALS detection…

Volume 28, Number 1 Technical Article by Dan Some and Amy Hanlon Characterizing Protein–Protein Interactions Via Static Light Scattering: Inhibition Kinetics and Dissociation Q uantification of the kinetic rates of protein association, dissociation, and aggregation is an essential factor in…

Protein Solutions™ Lens Protein: Conformational Changes Molar Mass vs. Volume LENPROT 1.0x10 7 UV detector response Molar mass Molar Mass (g/mol) 1.0x10 6 1.0x10 5 1.0x10 4 10.0 12.0 14.0 Volume (mL) 16.0 18.0 Figure 1. Marked changes in the…