High-throughput PROTAC compound screening workflow for targeted protein degradation on an Orbitrap Astral mass spectrometer with accurate label-free quantitation

Application note | AN003390 Omics A high-throughput PROTAC compound screening workflow for targeted protein degradation with the Orbitrap Astral mass spectrometer for accurate label-free quantitation Authors Abstract Kevin Yang, Tonya Pekar Hart, Targeted protein degradation (TPD) is an emerging and…

Single-Shot LC-MS Workflow for Comprehensive Proteome Identification on an Orbitrap Astral Mass Spectrometer Santosh Renuse1, Tabiwang N. Arrey2; Anna Pashkova2; Maowei Dou3; Jeff Op De Beeck4; Ryan Bomgarden3; Li Wang5; Qiong Wang5 ; Bernard Delanghe2; Xinyan Wu5, Sally Webb1 and…

P-II-0715 Discovering hidden depths: high-throughput proteomics study for enhanced biomarker discovery on Orbitrap Astral Mass Spectrometer Kevin Yang1, Amarjeet Flora2, Bhavin Patel2, Khatereh Motamedchaboki1, Stephanie Samra1, and Amirmansoor Hakimi1 1Thermo Fisher Scientific, San Jose, California, U.S.A. 2Thermo Fisher Scientific, Rockford,…

Mass spectrometry Rethink what is possible Orbitrap Astral mass spectrometer Rethink what is possible with novel technology Better understand biology and disease mechanisms with faster throughput, deeper coverage, higher sensitivity, and accurate and precise quantitation using the Thermo Scientific™ Orbitrap™…