Large scale purification – of oligonucleotides with ion exchange chromatography

Science with Passion SUMMARY 2450 1950 1450 950 450 -50 J. Wesolowski, Y. Krauke, G. Greco; [email protected] 0 2950 3 6 9 12 15 18 21 Time (min) 2450 Absorption (mAU) KNAUER Wissenschaftliche Geräte GmbH, Hegauer Weg 38, 14163 Berlin;…

Science with Passion Quality control of oligonucleotides using HPLC coupled to UV and MS detection J. Kramer1, U. Krop1, G. Greco1, T. Pöhlmann 2, C. Matthäus 2; [email protected] 1KNAUER Wissenschaftliche Geräte GmbH, Hegauer Weg 38, 14163 Berlin; www.knauer.net 2BianoGMP GmbH,…

Science with Passion Systematic and efficient method scale-up for peptide purification O OH H2N HO HN N N H2 H2N O O KNAUER Wissenschaftliche Geräte GmbH, Hegauer Weg 38, 14163 Berlin; www.knauer.net O NH H3C J. Menke, U. Krop, G.…

Science with Passion CBD purification – Part 1: Preparative HPLC method development in analytical scale and scale-up 2950 Absorption (mAU) 2450 SUMMARY 1450 950 450 -50 J. Wesolowski, Y. Krauke, G. Greco; [email protected] 0 2950 3 6 9 12 15…